483367-56-2 Usage
Description
Imidazo[1,2-b]pyridazine, 3,6-dichloro-2-(2-thienyl)is a heterocyclic chemical compound with the molecular formula C9H5Cl2N3S. It features a unique ring structure that incorporates nitrogen and sulfur atoms, along with dichloro and thienyl substituents. Imidazo[1,2-b]pyridazine, 3,6-dichloro-2-(2-thienyl)holds promise in pharmaceutical research and material science due to its potential applications and the specific properties conferred by its substituents.
Uses
Used in Pharmaceutical Research:
Imidazo[1,2-b]pyridazine, 3,6-dichloro-2-(2-thienyl)is utilized as a potential drug candidate for various therapeutic applications, primarily due to its antiviral and anticancer activities. Its unique structure allows it to be a subject of interest for the development of new treatments and therapies.
Used in Material Science and Organic Electronics:
Imidazo[1,2-b]pyridazine, 3,6-dichloro-2-(2-thienyl)is also studied for its potential use in the development of novel materials and organic electronics. The dichloro and thienyl substituents present in the imidazo[1,2-b]pyridazine ring may provide specific chemical and biological properties that make it a valuable component in advancing these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 483367-56-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,3,3,6 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 483367-56:
(8*4)+(7*8)+(6*3)+(5*3)+(4*6)+(3*7)+(2*5)+(1*6)=182
182 % 10 = 2
So 483367-56-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H5Cl2N3S/c11-7-3-4-8-13-9(6-2-1-5-16-6)10(12)15(8)14-7/h1-5H
483367-56-2Relevant articles and documents
Reactivity of 2-substituted imidazo[1,2-b]pyridazines: Preparation of 3-nitro, nitroso and chloro derivatives
Hervet, Maud,Galtier, Christophe,Enguehard, Cecile,Gueiffier, Alain,Debouzy, Jean-Claude
, p. 737 - 742 (2007/10/03)
The synthesis of 2-substitutedimidazo[1,2-b]pyridazines and their reactivity towards electrophilic substitutions are reported. The nitration was shown to be very dependent on the nature of the 2 substituent. Nitrosation using sodium nitrite in acetic acid media as a general method failed in all cases whereas chlorination was observed in warm hydrochloric acid. In order to ascertain the structure of some chloro derivatives, chlorination using N-chlorosuccinimide was also reported. Depending of the nature of the substituent, the reaction occurred at the C-3 imidazolic position and/or at the substituent on position 2. The 3-nitroso-2-phenyl derivative was finally obtained using an alternative synthetic pathway by direct condensation of 3-amino-6-chloropyridazine to ω-chloro-ω-nitrosoacetophenone. The structural determinations were ascertained using high field 1H and 13C-NMR.
