483367-60-8 Usage
Uses
Used in Organic Synthesis:
Imidazo[1,2-b]pyridazine, 6-chloro-3-nitroso-2-phenylis used as a key intermediate in organic synthesis for the creation of novel compounds with potential applications in various industries. Its unique structure and reactive functional groups make it a valuable building block for the development of new organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Imidazo[1,2-b]pyridazine, 6-chloro-3-nitroso-2-phenylis utilized as a potential pharmaceutical candidate. Its heterocyclic nature and the presence of various functional groups may contribute to the design of new drugs with specific therapeutic properties. Further research is required to explore its pharmacological potential and optimize its use in drug discovery.
Used in Materials Science:
Imidazo[1,2-b]pyridazine, 6-chloro-3-nitroso-2-phenylmay also find applications in materials science, where its unique structure and reactivity could be harnessed to develop new materials with specific properties. These materials could be used in various applications, such as sensors, catalysts, or advanced materials with tailored characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 483367-60-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,3,3,6 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 483367-60:
(8*4)+(7*8)+(6*3)+(5*3)+(4*6)+(3*7)+(2*6)+(1*0)=178
178 % 10 = 8
So 483367-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H7ClN4O/c13-9-6-7-10-14-11(8-4-2-1-3-5-8)12(16-18)17(10)15-9/h1-7H
483367-60-8Relevant academic research and scientific papers
Reactivity of 2-substituted imidazo[1,2-b]pyridazines: Preparation of 3-nitro, nitroso and chloro derivatives
Hervet, Maud,Galtier, Christophe,Enguehard, Cecile,Gueiffier, Alain,Debouzy, Jean-Claude
, p. 737 - 742 (2007/10/03)
The synthesis of 2-substitutedimidazo[1,2-b]pyridazines and their reactivity towards electrophilic substitutions are reported. The nitration was shown to be very dependent on the nature of the 2 substituent. Nitrosation using sodium nitrite in acetic acid media as a general method failed in all cases whereas chlorination was observed in warm hydrochloric acid. In order to ascertain the structure of some chloro derivatives, chlorination using N-chlorosuccinimide was also reported. Depending of the nature of the substituent, the reaction occurred at the C-3 imidazolic position and/or at the substituent on position 2. The 3-nitroso-2-phenyl derivative was finally obtained using an alternative synthetic pathway by direct condensation of 3-amino-6-chloropyridazine to ω-chloro-ω-nitrosoacetophenone. The structural determinations were ascertained using high field 1H and 13C-NMR.
