4839-08-1Relevant academic research and scientific papers
Effects of two-carbon bridge region methoxylation of benztropine: Discovery of novel chiral ligands for the dopamine transporter
Simoni, Daniele,Roberti, Marinella,Rondanin, Riccardo,Baruchello, Riccardo,Rossi, Marcello,Invidiata, Francesco Paolo,Merighi, Stefania,Varani, Katia,Gessi, Stefania,Borea, Pier Andrea,Marino, Silvia,Cavallini, Sabrina,Bianchi, Clementina,Siniscalchi, Anna
, p. 823 - 827 (2001)
6-Methoxylated and 8-oxygenated benztropines were prepared and evaluated for their DAT and SERT activity (binding and uptake inhibition). Methoxylation at the two-carbon bridge of benztropine produced a novel class of potent and selective DAT ligands. An
