484008-63-1

Upstream product

• 7298-67-1 5-acetamido-2-hydroxyacetophenone 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 80881-78-3 6-amino-2-(4-methoxyphenyl)-4H-chromen-4-one 
• 80881-76-1 N-(2-(4-methoxyphenyl)-4-oxo-4H-chromen-6-yl)acetamide 

Relevant academic research and scientific papers

2-ARYL AND 2-HETEROARYL 4H-1-BENZOPYRAN-4-ONE-6-AMIDINO DERIVATIVES, NEW PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF ARTHRITIS, CANCER AND RELATED PAIN

2-aryl and 2-heteroaryl 4h-1-benzopyran-4-one-6-amidino derivatives of formula (I) useful as pharmacological agents for the treatment of arthritis, cancer and related pain.

2-ARYL AND 2 -HETEROARYL 4H-1-BENZOPYRAN-4-ONE-6-AMIDINO DERIVATIVES FOR THE TREATMENT OF ARTHRITIS, CANCER AND RELATED PAIN

2-aryl and 2-heteroaryl 4h-1-benzopyran-4-one-6-amidino derivatives of formula (I) useful as pharmacological agents for the treatment of arthritis, cancer and related pain.

Synthesis and microbial activity of new 1,4-benzothiazines bearing paracetamol moiety

5-Acetamido-2-hydroxyacetophenone 1 on condensation with aroyl/heteroyl chlorides in pyridine gives esters, 2-acyl-4-acetamidophenyl aroylates / heteroylates 2 which are subjected to B.V. transformation to get 1-aryl-3-[2′-hydroxy-5′-acetamidophenyl]-1,3-propanediones 3. The 1,3-propanediones 3 when condensed with 2-aminobenzenethiols in dimethyl sulfoxide yield the title compounds, 2-[2′-hydroxy-5′-acetamidobenzoyl]-3-aryl/heteryl7- substituted-4H-1,4-benzothiazines 4. The microbial activity of the title compounds has been evaluated.