4841-20-7

Basic information

• Product Name: SILVEX METHYL ESTER
• Synonyms: SILVEX METHYL ESTER;Methyl 2-(2,4,5-trichlorophenoxy)propanoate;Methyl 2-(2,4,5-trichlorophenoxy)propionate;methyl2-(2,4,5-trichlorophenoxy)propanoicacid;propanoicacid,2-(2,4,5-trichlorophenoxy)-,methylester;Propionic acid, 2-(2,4,5-trichlorophenoxy)-, methyl ester;FENOPROP-METHYL ESTER;2-(2,4,5-TRICHLOROPHENOXY)-PROPIONIC ACID METHYLESTER
• CAS NO: 4841-20-7
• Molecular Formula: C10H9Cl3O3
• Molecular Weight: 283.54
• EINECS: 203-777-6
• Product Categories: Alpha sort;Pesticides&Metabolites;Q-ZAlphabetic;S;SA - SM
• Mol File: 4841-20-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 337.3°Cat760mmHg
• Flash Point: -26 °C
• Appearance: /
• Density: 1.399g/cm³
• Vapor Pressure: 0.000106mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: 2-8°C
• BRN: 2135850
• CAS DataBase Reference: SILVEX METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: SILVEX METHYL ESTER(4841-20-7)
• EPA Substance Registry System: SILVEX METHYL ESTER(4841-20-7)

Safety Data

• Hazard Codes: Xn,N,F
• Statements: 22-36-67-65-50/53-38-62-51/53-48/20-11
• Safety Statements: 26-36/37-62-61-60-33-29-16-9
• RIDADR: 2588
• WGK Germany: 3
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 4841-20-7(Hazardous Substances Data)

Usage

Uses

2,4,5-TP methyl ester

InChI:InChI=1/C10H9Cl3O3/c1-5(10(14)15-2)16-9-4-7(12)6(11)3-8(9)13/h3-5H,1-2H3

Upstream product

• 67-56-1 methanol 
• 93-72-1 2-(2,4,5-trichlorophenoxy)propanoic acid 
• 55746-49-1 2-(2,4,5-trichloro-phenoxy)-propionyl chloride 

Downstream Products

• 1383565-67-0 2-(2,4,5-trichlorophenoxy)-N'-(1-p-tolylethylidene)propanehydrazide 
• 1383565-68-1 2-(2,4,5-trichlorophenoxy)-N'-(1-(4-chlorophenyl)ethylidene)propanehydrazide 
• 1383565-69-2 2-(2,4,5-trichlorophenoxy)-N'-(2-oxoindolin-3-ylidene)propanehydrazide 
• 1383565-70-5 2-(2,4,5-trichlorophenoxy)-N'-(2-oxo-1-(prop-2-ynyl)indolin-3-ylidene)propanehydrazide 
• 1383565-71-6 2-(2,4,5-trichlorophenoxy)-N-(2-(3-nitrophenyl)-4-oxothiazolidin-3-yl)propanamide 
• 1383565-72-7 2-(2,4,5-trichlorophenoxy)-N-(4-oxo-2-(thiophen-2-yl)thiazolidin-3-yl)propanamide 
• 1383565-73-8 2-(2,4,5-trichlorophenoxy)-N-(2-(5-methylthiophen-2-yl)-4-oxothiazolidin-3-yl)propanamide 
• 1383565-74-9 2-(2,4,5-trichlorophenoxy)-N-(2-(5-methylfuran-2-yl)-4-oxothiazolidin-3-yl)propanamide 
• 1383565-75-0 2-(2,4,5-trichlorophenoxy)-N-(4-oxo-2-(pyridin-3-yl)thiazolidin-3-yl)propanamide 
• 1383565-76-1 2-(2,4,5-trichlorophenoxy)-N-(4-oxo-2-(pyridin-4-yl)thiazolidin-3-yl)propanamide 
• 1383565-77-2 2-(2,4,5-trichlorophenoxy)-N-(2-methyl-4-oxo-2-p-tolylthiazolidin-3-yl)propanamide 
• 1383565-78-3 2-(2,4,5-trichlorophenoxy)-N-(2-(4-chlorophenyl)-2-methyl-4-oxothiazolidin-3-yl)propanamide 
• 1383565-79-4 2-(2,4,5-trichlorophenoxy)-N-(2,4'-dioxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidin]-3'-yl)propanamide 
• 1383565-80-7 2-(2,4,5-trichlorophenoxy)-N-(2,4'-dioxo-1-(prop-2-ynyl)-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3]thiazolidin]-3'-yl)propanamide 

Relevant articles and documents

Design, synthesis and molecular modelling of novel 4-thiazolidinones of potential activity against Gram positive bacteria

A series of novel 4-thiazolidinones (2-21) incorporating 2-(2,4,5-trichlorophenoxy)propanamide was synthesised. Reaction of 2-(2,4,5-trichlorophenoxy)propanohydrazide (1) with the corresponding carbonyl compounds afforded 2-(2,4,5-trichlorophenoxy)propanehydrazide hydrazones (2-11) which upon reaction with thioglycolic acid revealed 4-thiazolidinone derivatives (12-21). Structure elucidation of the synthesised compounds was done based on analytical and spectral data. The newly synthesised compounds were evaluated for their antimicrobial activity. Compounds 13 and 17 showed the equipotent activity with MIC value 6.25 μg ml-1 compared with chloramphenicol as reference drug. Docking studies of the promising compounds was done on MurB using Dock6.4 docking program to study their observed activity.