484670-87-3Relevant academic research and scientific papers
Synthesis and antibacterial activity of novel C12 ethyl ketolides
Burger, Matthew T.,Hiebert, Christy,Seid, Mehran,Chu, Daniel T.,Barker, Lynn,Langhorne, Mike,Shawar, Ribhi,Kidney, Jolene,Desai, Manoj C.,Plattner, Jacob J.
, p. 5592 - 5604 (2007/10/03)
A novel series of C12 ethyl erythromycin derivatives have been discovered which exhibit in vitro and in vivo potency against key respiratory pathogens, including those resistant to erythromycin. The C12 modification involves replacin
PYRIDYL SUBSTITUTED KETOLIDE ANTIBIOTICS
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Page 123; 124, (2010/02/09)
Antimicrobial macrolide and ketolide compounds are provided having formulas (XII), as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.
