4852-00-0Relevant academic research and scientific papers
Gold catalyzed efficient preparation of dihydrobenzofuran from 1,3-enyne and phenol
Wang, Yu-Jiang,Zhang, Yuan,Qiang, Zou,Liang, Jia-Ying,Chen, Zili
supporting information, p. 12607 - 12610 (2021/12/07)
A gold catalyzed formal intermolecular [2+3] cyclo-coupling of 1,3-enynes with phenols was developed to prepare dihydrobenzofuran derivatives with the addition of 2,6-dichloropyridine N-oxide, in which, a highly ortho-selective phenol SEAr functionalizati
Cobalt-Catalyzed gem-Cross-Dimerization of Terminal Alkynes
Chen, Jia-Feng,Li, Changkun
, p. 3881 - 3889 (2020/03/26)
Transition-metal-catalyzed dimerization of two different terminal alkynes provides an atom-economic synthesis of valuable conjugated 1,3-enynes. Despite many catalyst systems developed, the state-of-the-art solutions are still limited to special alkynes. A practical catalyst, which could be used to cross-dimerize general aryl alkynes and aliphatic alkynes, is still highly desired. Herein we present the earth-abundant Co(II)-catalyzed highly gem-selective cross-dimerization of aryl alkynes and aliphatic alkynes or gas acetylene under mild reaction conditions. Conjugated 1,3-enynes with various useful functional groups can be prepared in high yields. The application of Co(OAc)2 and t-butyl group substituted triphos ligand is essential to distinguish the alkynes at different steps and realize the gem-selectivity.
Direct access to pentenedinitriles: Via Ni-catalyzed dihydrocyanation of 1,3-enynes
Fang, Xianjie,Gao, Jihui,Sun, Feilong
supporting information, p. 6858 - 6861 (2020/07/04)
A highly regio-and stereoselective dihydrocyanation of 1,3-enynes was implemented by nickel/diphosphine catalysts. This reaction represents the first example of Ni-catalyzed dihydrocyanation of 1,3-enynes using TMSCN and MeOH as HCN surrogates. In this tr
Regioselective solvent-dependent benzannulation of conjugated enynes
Puenner, Florian,Hilt, Gerhard
supporting information; experimental part, p. 3617 - 3619 (2012/05/20)
The transformation of enynes under cobalt-catalysis leads to symmetrical benzannulation products in dichloromethane. In tetrahydrofuran the cobalt-catalysed reactions afforded the unprecedented unsymmetrical benzannulation products in moderate to good yields and good regioselectivities. In addition, cyclotrimerisation of the alkyne subunit can be realised when electron-deficient enynes are applied in the cobalt-catalysed transformations to generate 1,2,4-trivinylbenzene derivatives using tetrahydrofuran as solvent.
Concerted vs stepwise mechanisms in dehydro-Diels-Alder reactions
Ajaz, Aida,Bradley, Alexander Z.,Burrell, Richard C.,Li, William Hoi Hong,Daoust, Kimberly J.,Bovee, Laura Boddington,Dirico, Kenneth J.,Johnson, Richard P.
experimental part, p. 9320 - 9328 (2012/01/03)
The Diels-Alder reaction is not limited to 1,3-dienes. Many cycloadditions of enynes and a smaller number of examples with 1,3-diynes have been reported. These "dehydro"-Diels-Alder cycloadditions are one class of dehydropericyclic reactions which have lo
