485755-38-2

Basic information

• Product Name: 3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-hydroxyallyl)-1,2-di-O-isopropylidene-α-D-ribofuranose
• Synonyms: 3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-hydroxyallyl)-1,2-di-O-isopropylidene-α-D-ribofuranose
• CAS NO: 485755-38-2
• Molecular Weight: 466.574
• Mol File: 485755-38-2.mol

Chemical Properties

• CAS DataBase Reference: 3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-hydroxyallyl)-1,2-di-O-isopropylidene-α-D-ribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-hydroxyallyl)-1,2-di-O-isopropylidene-α-D-ribofuranose(485755-38-2)
• EPA Substance Registry System: 3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-hydroxyallyl)-1,2-di-O-isopropylidene-α-D-ribofuranose(485755-38-2)

Safety Data

• Hazardous Substances Data: 485755-38-2(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 457068-00-7 3-C-allyl-3,5-di-O-benzyl-4-C-hydroxymethyl-1,2-di-O-isopropylidene-α-D-ribofuranose 
• 457067-99-1 3-C-allyl-3-O-benzyl-4-C-hydroxymethyl-1,2-O-isopropylidene-α-D-erythro-pentofuranose 
• 197702-06-0 3-C-allyl-3-O-benzyl-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 136152-95-9 (3aR,5S,6R,6aR)-6-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 
• 100-39-0 benzyl bromide 

Downstream Products

• 485755-41-7 1-(2-O-acetyl-3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-(benzoyloxy)allyl)-β-D-ribofuranosyl)thymine 
• 485755-42-8 (1S,5S,6S,8R,9R)-9-acetyloxy-5-(benzoyloxy)-1-(benzyloxy)-6-[(benzyloxy)methyl]-8-(thymin-1-yl)-7-oxabicyclo[4.3.0]non-3-ene 
• 485755-40-6 1,2-di-O-acetyl-3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-(benzoyloxy)allyl)-α/β-D-ribofuranose 
• 485755-43-9 (1S,5S,6S,8R,9R)-1-(benzyloxy)-6-[(benzyloxy)methyl]-5,9-dihydroxy-8-(thymin-1-yl)-7-oxabicyclo[4.3.0]non-3-ene 
• 696599-35-6 (1S,3R,7R,8S,12S)-8-(benzyloxy)-1-[(benzyloxy)methyl]-5,5-dimethyl-12-hydroxy-2,4,6-trioxatricyclo[6.4.0.0^3,7]dodec-10-ene 
• 485755-39-3 3-C-allyl-3,5-di-O-benzyl-4-C-(1(S)-(benzoyloxy)allyl)-1,2-di-O-isopropylidene-α-D-ribofuranose 

Relevant articles and documents

A ring-closing metathesis based synthesis of bicyclic nucleosides locked in S-type conformations by hydroxyl functionalised 3′,4′-trans linkages

A [4.3.0]bicyclic nucleoside that contains an unsaturated hydroxylated 3′,4′-trans linkage has been efficiently synthesised. Thus, from diacetone-D-glucose as the starting material, stereoselective Grignard reactions for the introduction of allyl groups,

3′,4′-trans-Linked bicyclic nucleosides locked in S-type conformations

A novel class of 3′,4′-trans-linked bicyclic nucleosides with locked S-type furanose conformations is introduced by synthesis of two model derivatives; one was obtained by cyclic ether formation and the other by ring-closing metathesis methodology.