485819-20-3

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 6802-76-2 ethyl 2-cyano-2-cyclohexylideneacetate 

Downstream Products

• 485819-38-3 2,6-bis(4-chlorophenyl)-4-cyano-4-ethoxycarbonyl-4H-pyran 
• 485819-32-7 2,6-bis(4-chlorophenyl)-4-cyano-4-ethoxycarbonyl-4H-thiopyran 
• 485819-26-9 2,6-bis(4-chlorophenyl)-4-cyano-4-ethoxycarbonyl-1,4-dihydropyridine 
• 753454-09-0 4-(4-chloro-phenyl)-2-[2-(4-chloro-phenyl)-2-oxo-ethyl]-4-oxo-butyric acid methyl ester 
• 753454-21-6 2,6-bis-(4-chloro-phenyl)-4H-pyran-4-carboxylic acid methyl ester 
• 172282-81-4 4-(4-chloro-phenyl)-2-[2-(4-chloro-phenyl)-2-oxo-ethyl]-4-oxo-butyric acid 

Relevant academic research and scientific papers

Regioselective alkylation of isopropylidene- and cyclohexylidenepropanedinitrile with phenacyl bromides

Alkylation of isopropylidene- and cyclohexylidenepropanedinitrile with phenacyl bromides gave 2,2-bis(2-aryl-2-oxoethyl)propanedinitriles. Direct alkylation of propanedinitrile with phenacyl bromides afforded only 2-(2-aryl-2-oxoethyl)propanedinitriles.

Regioselective reactions of phenacyl bromide with active methylene compounds

The reactivity of phenacyl bromide with active methylene compounds in the presence of alcoholic KOH, BTEAC (PTC), NaOEt and K2CO3 has been studied.

3,3-Disubstituted 1,5-diaryl-1,5-pentanediones as versatile intermediates for spiro heterocycles

The spiro heterocycles, spiro-4H-pyran pyrazolidinedione/isoxazolidinedione/pyrimidinetrione/thioxopyrimidinedione and spiro-4H-pyran aminopyrazolidinone/isoxazolidinone/hydroxypyrimidinone/mercaptopyrimidinone have been prepared from 3,3-disubstituted 1,5-diaryl-1,5-pentanedione. All the compounds have been characterised by spectral parameters.