485819-34-9

Upstream product

• 108-59-8 malonic acid dimethyl ester 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 485819-17-8 2,2-bis-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-malonic acid dimethyl ester 

Downstream Products

• 485819-28-1 2,6-bis(4-methoxyphenyl)-4,4-dimethoxycarbonyl-4H-thiopyran 

Relevant academic research and scientific papers

3,3-Disubstituted 1,5-diaryl-1,5-pentanediones as versatile intermediates for spiro heterocycles

The spiro heterocycles, spiro-4H-pyran pyrazolidinedione/isoxazolidinedione/pyrimidinetrione/thioxopyrimidinedione and spiro-4H-pyran aminopyrazolidinone/isoxazolidinone/hydroxypyrimidinone/mercaptopyrimidinone have been prepared from 3,3-disubstituted 1,5-diaryl-1,5-pentanedione. All the compounds have been characterised by spectral parameters.

2,6-Diaryl-4,4-disubstituted-4H-thiopyran: Source for spiro heterocycles

The 1,5-diaryl-3,3-disubstituted-1,5-pentanedione on reaction with ammonium acetate, phosphorus pentoxide and phosphorus pentasulfide gave respective 1,4-dihydropyridine, 4H-pyran and 4H-thiopyran. Novel spiro heterocycles have been obtained by the cyclocondensation of 4H-thiopyran with hydrazine, hydroxylamine, urea and thiourea.