485835-59-4

Basic information

• Product Name: Carbamic acid, [(1S)-3-(methylthio)-1-(1-pyrrolidinylcarbonyl)propyl]-, 1,1-dimethylethyl ester
• CAS NO: 485835-59-4
• Molecular Formula: C14H26N2O3S
• Molecular Weight: 302.438
• Mol File: 485835-59-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-3-(methylthio)-1-(1-pyrrolidinylcarbonyl)propyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-3-(methylthio)-1-(1-pyrrolidinylcarbonyl)propyl]-, 1,1-dimethylethyl ester(485835-59-4)
• EPA Substance Registry System: Carbamic acid, [(1S)-3-(methylthio)-1-(1-pyrrolidinylcarbonyl)propyl]-, 1,1-dimethylethyl ester(485835-59-4)

Safety Data

• Hazardous Substances Data: 485835-59-4(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 1093981-22-6 2-azido-1-(4-fluorobenzyl)-1H-benzo[d]imidazole 

Relevant articles and documents

Water compatible photoarylation of amino acids and peptides

A novel photoarylation of amino acids and peptides is described, which tolerates the presence of water. Irradiation of Boc-protected amino acids in the presence of N-protected 2-azidobenzimidazoles leads to selective arylation of carboxy termini or side chains. The new reaction also works for peptides. Irradiation of the nonapeptide H-SPSYVYHQF-OH also resulted in selective arylation of the tyrosine side chains, as indicated by ESI-MS/MS fragmentation. Chemo- and regioselectivity could add the title reaction to the repertoire of photoaffinity labeling methods.