485843-93-4Relevant academic research and scientific papers
Formaldehyde-induced DNA cross-link of indolizino[1,2-b]quinolines derived from the A-D rings of camptothecin
Perzyna, Aurore,Marty, Carine,Facompré, Michael,Goossens, Jean-Fran?ois,Pommery, Nicole,Colson, Pierre,Houssier, Claude,Houssin, Raymond,Hénichart, Jean-Pierre,Bailly, Christian
, p. 5809 - 5812 (2002)
Camptothecin consists of a lactone E ring adjacent to tetracyclic A-D rings of a planar chromophore, which are essential for topoisomerase I inhibition and DNA interaction. The A-D rings can be exploited to develop DNA-sequence-reading molecules. Indolizi
