485845-75-8Relevant academic research and scientific papers
Synthesis of enantiomerically pure P-stereogenic diphosphacrowns and their palladium complexes
Morisaki, Yasuhiro,Imoto, Hiroaki,Hirano, Koji,Hayashi, Tamio,Chujo, Yoshiki
supporting information; experimental part, p. 1795 - 1803 (2011/06/17)
A practical synthetic route for enantiomerically pure P-stereogenic diphosphacrowns was developed by using a P-stereogenic bisphosphine as a chiral building block. Their molecular structures were confirmed by NMR spectroscopy and X-ray crystallography. Complexation of the diphosphacrowns with palladium was carried out, and the corresponding palladium complexes were obtained. The P-stereogenic diphosphacrowns were applicable to the chiral ligand for the asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated ketone catalyzed by palladium. This reaction proceeded smoothly to afford the corresponding 1,4-addition products in high yield with good enantioselectivities.
Practical synthesis of P-stereogenic diphosphacrowns
Morisaki, Yasuhiro,Imoto, Hiroaki,Tsurui, Kazuhiko,Chujo, Yoshiki
supporting information; experimental part, p. 2241 - 2244 (2009/10/23)
P-Stereogenic 18-diphosphacrown-6 derivatives containing a chiral bisphosphine unit were synthesized. This is the first practical method for the synthesis of optically pure diphosphacrowns. The diphosphacrowns have the structure of a chiral figure "8" wit
