486422-05-3

Basic information

• Product Name: 3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester
• Synonyms: 3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester;Benzenesulfonamide, N,N-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;3-(N,N-DiMethylsulfaMoyl)phenylboronic acid, pinacol ester;N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide
• CAS NO: 486422-05-3
• Molecular Formula: C₁₄H₂₂BNO₄S
• Molecular Weight: 311.2
• Product Categories: Aryl;Organoborons
• Mol File: 486422-05-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 432.1±47.0 °C(Predicted)
• Appearance: /
• Density: 1.18±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -4.74±0.70(Predicted)
• CAS DataBase Reference: 3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester(486422-05-3)
• EPA Substance Registry System: 3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester(486422-05-3)

Safety Data

• Hazardous Substances Data: 486422-05-3(Hazardous Substances Data)

Usage

General Description

3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester is a chemical compound that is commonly used in organic synthesis. It is a boronic acid pinacol ester, which means it contains a boronic acid group attached to a pinacol ester moiety. 3-(N,N-Dimethylaminosulfonyl)phenylboronic acid pinacol ester is known for its ability to react with a variety of organic compounds, making it a versatile reagent in the field of organic chemistry. It is often used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it has been studied for its potential applications in the development of new materials and as a catalyst in various chemical reactions.

Upstream product

• 14417-01-7 N,N-dimethylbenzenesulfonamide 
• 73183-34-3 bis(pinacol)diborane 
• 153435-80-4 3-bromo-N,N-dimethyl-benzenesulfonamide 
• 2905-24-0 3-Bromobenzenesulfonyl chloride 

Downstream Products

• 1152473-60-3 N,N-dimethyl-3-(2-(4-morpholinophenylamino)thieno[3,2-d]pyrimidin-7-yl)benzenesulfonamide 

Relevant articles and documents

Meta Selective C-H Borylation of Sterically Biased and Unbiased Substrates Directed by Electrostatic Interaction

An electrostatically directed meta borylation of sterically biased and unbiased substrates is described. The borylation follows an electrostatic interaction between the partially positive and negative charges between the ligand and substrate. With this strategy, it has been demonstrated that a wide number of challenging substrates, especially 4-substituted substrates, can selectively be borylated at the meta position. Moreover, unsubstituted substrates also displayed excellent meta selectivity. The reaction employs a bench-stable ligand and proceeds at a milder temperature, precluding the need to synthesize a bulky and sophisticated ligand/template.

HSD17B13 INHIBITORS AND USES THEREOF

Described herein are HSD17B13 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of liver disease, metabolic disease, or cardiovascular disease, such as NAFLD or NASH,