486999-69-3Relevant academic research and scientific papers
Synthesis of new MKC-442 analogues containing alkenyl chains or reactive functionalities at C-5
Petersen, Lene,Hansen, Thomas H.,Khalifa, Nagy M.,Jorgensen, Per T.,Pedersen, Erik B.,Nielsen, Claus
, p. 1031 - 1043 (2002)
In an effort to obtain more insight into the interaction between HIV-1 reverse transcriptase (RT) and MKC-442 analogues, a new series of compounds was synthesized and evaluated for inhibition of HIV-1 replication. The modifications include bulky alkenyl s
