487048-28-2

Basic information

• Product Name: N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER
• Synonyms: N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER;BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER;N-Boc-cis-4-cyano-D-prolinemethylester;cis-N-Boc-4-cyano-L-proline Methyl ester, 97%;(2S,4S)-1-tert-butyl 2-Methyl 4-cyanopyrrolidine-1,2-dicarboxylate;1,2-Pyrrolidinedicarboxylic acid, 4-cyano-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4S)-;(2R,4S)-1-tert-butyl 2-Methyl 4-cyanopyrrolidine-1,2-dicarboxylate;(2S,4S)-4-Cyano-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) 2-methyl ester
• CAS NO: 487048-28-2
• Molecular Formula: C₁₂H₁₈N₂O₄
• Molecular Weight: 254.28
• Mol File: 487048-28-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 366.4±42.0 °C(Predicted)
• Appearance: /
• Density: 1.17
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -5.81±0.60(Predicted)
• CAS DataBase Reference: N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER(487048-28-2)
• EPA Substance Registry System: N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER(487048-28-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 487048-28-2(Hazardous Substances Data)

Usage

General Description

N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER is a chemical compound used in organic synthesis and medicinal chemistry. It is a derivative of proline, an amino acid, and contains a BOC (tert-butoxycarbonyl) protecting group, a cyano group, and a methyl ester group. N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER is commonly used as a building block in the synthesis of pharmaceuticals and other biologically active molecules. It can also be used as a chiral catalyst in asymmetric synthesis reactions. N-BOC-CIS-4-CYANO-L-PROLINE METHYL ESTER is a valuable reagent for the preparation of complex molecules with specific stereochemistry and functional groups.

Upstream product

• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 

Downstream Products

• 132622-71-0 (2S,4S)-4-cyano-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 
• 1256389-46-4 (2S,4S)-2-[5-(4-bromo-phenyl)-1H-imidazol-2-yl]-4-cyano-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1256390-80-3 (2S,4S)-4-cyano-2-{5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-1H-imidazol-2-yl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1399845-10-3 (2S,4S)-4-Cyano-2-(5-{4'-[2-((2S,5S)-5-methoxycarbonylamino-4-oxo-1,2,4,5,6,7-hexahydro-azepino[3,2,1-hi]indol-2-yl)-3H-imidazol-4-yl]-biphenyl-4-yl}-1H-imidazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1399845-11-4 [(2S,5S)-2-(5-{4'-[2-((2S,4S)-4-cyano-pyrrolidin-2-yl)-3H-imidazol-4-yl]-biphenyl-4-yl}-1H-imidazol-2-yl)-4-oxo-1,2,4,5,6,7-hexahydro-azepino[3,2,1-hi]indol-5-yl]-carbamic acid methyl ester hydrochloride 
• 1399845-08-9 {(2S,5S)-2-[5-(4'-{2-[(2S,4S)-4-cyano-1-((S)-2-methoxycarbonylamino-3-methyl-butyryl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-biphenyl-4-yl)-1H-imidazol-2-yl]-4-oxo-1,2,4,5,6,7-hexahydro-azepino[3,2,1-hi]indol-5-yl}-carbamic acid methyl ester 
• 1399845-09-0 (2S,4S)-4-cyano-pyrrolidine-1,2-dicarboxylic acid 2-[2-(4-bromo-phenyl)-2-oxo-ethyl]ester 1-tert-butyl ester 
• 1256389-46-4 (2S,4S)-2-[4-(4-bromo-phenyl)-1H-imidazol-2-yl]-4-cyano-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1433280-48-8 [(S)-1-((2S,4S)-4-cyano-2-{4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-1H-imidazol-2-yl}-pyrrolidine-1-carbonyl)-2-methyl-propyl]-carbamic acid methyl ester 
• 1256389-47-5 ((S)-1-{(2S,4S)-2-[4-(4-bromo-phenyl)-1H-imidazol-2-yl]-4-cyano-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester 
• 1433281-23-2 ((S)-1-{(2S,4S)-4-carbamoyl-2-[4-(5'-chloro-4'-{[6-((R)-2-methyl-piperazin-1-yl)-pyridine-3-carbonyl]-amino}-2'-trifluoromethoxy-biphenyl-4-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester 
• 1378391-42-4 (2S,4S)-2-(2-(9-bromo-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 1-tert-butyl 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate 
• 1378391-43-5 (2R,4R)-1-tert-butyl 2-(2-(9-((2S,5S)-1-((S)-2-(methoxycarbonylamino)-3-methylbutanoyl)-5-methylpyrrolidine-2-carbonyloxy)-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate 
• 1378391-44-6 tert-butyl (2S,4S)-2-[5-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,4,5,11-tetrahydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate 

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