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Phenyl(trifluoromethyl)phosphine, also known as trifluoromethylphenylphosphine, is an organophosphorus compound with the chemical formula C6H5P(CF3)2. It is a colorless liquid that is sensitive to air and moisture, and it is used as a reagent in organic synthesis. phenyl(trifluoromethyl)phosphine is characterized by its phosphorus atom bonded to a phenyl group and two trifluoromethyl groups, which contribute to its unique chemical properties. It is synthesized through the reaction of trifluoromethyllithium with diphenylchlorophosphine and is employed in the preparation of various phosphorus-containing compounds, such as phosphine oxides and phosphines. Due to its reactivity, it is typically handled under an inert atmosphere and is stored away from light and heat.

4872-36-0

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4872-36-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4872-36-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,7 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4872-36:
(6*4)+(5*8)+(4*7)+(3*2)+(2*3)+(1*6)=110
110 % 10 = 0
So 4872-36-0 is a valid CAS Registry Number.

4872-36-0Downstream Products

4872-36-0Relevant academic research and scientific papers

P-stereogenic ferrocene-based (Trifluoromethyl)phosphanes: Synthesis, structure, coordination properties and catalysis

Sondenecker, Aline,Cvengros, Jan,Aardoom, Raphael,Togni, Antonio

, p. 78 - 87 (2011)

Diastereoselective ortho-hydroxymethylation of (R)-(1-ferrocenylethyl) dimethylamine and Bronsted-acid-mediatednucleophilic substitution with phenyl(trifluoromethyl)phosphane affords an epimeric mixture of P-stereogenic amine-phosphanes 4a and 4b, which a

Recent advances in electrophilic CF3-transfer using hypervalent iodine(III) reagents

Kieltsch, Iris,Eisenberger, Patrick,Stanek, Kyrill,Togni, Antonio

scheme or table, p. 260 - 263 (2009/04/07)

The development of new methodologies for an efficient introduction of CF3 groups into complex molecules constitutes one of the most challenging tasks of modern organic chemistry. Recently, we reported the access to a new class of electrophilic CF3-transfer reagents based on hypervalent iodine. The versatile application of these reagents to C-centred nucleophiles, such as β-keto esters, silyl enol ethers and α-nitro esters, as well as to thiols and primary and secondary phosphines is described. Experiments with phenols afforded corresponding trifluomethylethers in very low yields. Schweizerische Chemische Gesellschaft.

Mild electrophilic trifluoromethylation of secondary and primary aryl- and alkylphosphines using hypervalent iodine(III)-CF3 reagents

Eisenberger, Patrick,Kieltsch, Iris,Armanino, Nicolas,Togni, Antonio

, p. 1575 - 1577 (2008/12/21)

A direct, mild and efficient trifluoromethylation of primary and secondary phosphines is achieved with easily accessible, cheap hypervalent iodine compounds acting as electrophilic CF3-transfer reagents. The Royal Society of Chemistry.

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