488-70-0

Usage

Synthesis Reference(s)

Synthetic Communications, 10, p. 195, 1980 DOI: 10.1080/00397918008064222

InChI:InChI=1/C10H14O/c1-6-5-10(11)9(4)8(3)7(6)2/h5,11H,1-4H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 137-18-8 2,5-Dimethyl-1,4-benzoquinone 
• 132912-52-8 3,4,5-Trimethyl-2-piperidinomethyl-phenol 
• 41827-90-1 4-hydroxy-2,3,6-trimethylbenzaldehyde 
• 20315-34-8 2,3,4,5-tetramethyl-anisole 
• 2217-45-0 2,3,4,5-tetramethylaniline 
• 488-23-3 1,2,3,4-Tetramethylbenzene 
• 77-74-7 3-methylpentan-3-ol 
• 108-24-7 acetic anhydride 
• 91-22-5 quinoline 
• 20805-00-9 6-methoxy-2,3,4-trimethyl-benzaldehyde 
• 90416-29-8 2-chloro-3,5,6-trimethylphenol 
• 19447-00-8 4-methoxy-2,6-dimethylbenzylaldehyde 
• 40101-36-8 1-Bromo-2,3,4,5-tetramethylbenzene 

Downstream Products

• 94962-33-1 3,4,5,6,3',4',5',6'-octamethyl-2,2'-methanediyl-di-phenol 
• 91799-53-0 2-bromo-3,4,5,6-tetramethyl-phenol 
• 34059-80-8 6-Acetoxy-3,4,5,6-tetramethylcyclohexa-2,4-dienon 
• 30075-65-1 6-Nitro-2,3,4,5-tetramethylbenzylchlorid 
• 51566-93-9 O-(2,3,4,5-tetramethylphenyl)benzoin 
• 20315-34-8 2,3,4,5-tetramethyl-anisole 
• 6671-62-1 O-Methyl-5-hydroxy-1,2,3,4-benzenetetracarboxylicsaeure-tetramethylester 
• 128540-70-5 2,3,4,5-tetramethyl-3-nitro-6-oxocyclohexa-1,4-dienecarbonitrile 
• 128540-71-6 3-hydroxy-2,3,4,5-tetramethyl-6-oxocyclohexa-1,4-dienecarbonitrile 
• 128540-69-2 2-hydroxy-3,4,5,6-tetramethylbenzonitrile 
• 51571-07-4 2-Aminomethyl-3,4,5,6-tetramethyl-phenol; hydrochloride 
• 121099-79-4 7-(4-Fluoro-phenyl)-7-(2-hydroxy-3,4,5,6-tetramethyl-phenyl)-heptanoic acid 
• 60368-01-6 acetic acid-(2,3,4,5-tetramethyl-phenyl ester) 
• 25140-67-4 (2,3,4,5-tetramethyl-phenoxy)-acetic acid 

Relevant academic research and scientific papers

Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols

A process for making a compound of the formula

Photochemical Transformationos of Protonated Phenols. A One-Step Synthesis of Umbellulone from Thymol

UV irradiation of thymol (7) at 254 or 300 nm in trifluoromethanesulfonic acid affords ten products, eight of which have been isolated and characterized.Four competitive processes are suggested to be operating in the formation of the photoproducts: (i) regioselective type A rearrangement leading to umbellulone (8, about 10percent, (ii) formal C2->C3 migration by type A rearrangement and ring opening which affords the principal products, 3-isopropyl-5-methylphenol (12, 17percent), (iii) intermolecular transalkylation leading to diisopropylphenols 13-15 (17percent), and (iv) formation ofpiperitenone (10, 5percent) initiated by hydrogen abstraction.A mechanism for the formation of 10 is proposed.Both para- and ortho-protonated 7 are suggested to be involved in product formation.