488085-92-3Relevant academic research and scientific papers
Synthesis of 6-chloro-9-methyl-/7-methoxyphenothiazines via Smiles rearrangement
Gupta, Kalpana,Gupta, Rajni,Gupta,Kumar
, p. 265 - 270 (2007/10/03)
6-Chloro-9-methyl-/7-methoxyphenothiazines have been synthesized via Smiles rearrangement of 6-chloro-3-methyl-/5-methoxy-2-formamido-2′-nitrodiphenyl sulfides. The formyl derivatives were obtained by the formylation of diphenyl sulfides which were prepared by the condensation of 2-amino-6-chloro-3-methyl-/5-methoxybenzenethiols with o-halonitrobenzenes. With halonitrobenzene having nitro group at both the ortho positions to the reactive halogen atom, 1-nitrophenothiazines are obtained in a single step as Smiles rearrangement occurs in situ.
