Propargyl-PEG1-t-butyl ester is a chemical compound characterized by the presence of a propargyl group and a t-butyl protected carboxyl group. This molecule is notable for its ability to engage in copper-catalyzed azide-alkyne Click Chemistry, which allows it to form a stable triazole linkage. Additionally, the t-butyl protected carboxyl group can be deprotected under acidic conditions, making it a versatile compound for various applications.
488150-84-1
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Basic information
- Product Name: Propargyl-PEG1-t-butyl ester
- Synonyms: Propargyl-PEG1-t-butyl ester;Alkyne-PEG1-CH2CH2COOtBu
- CAS NO:488150-84-1
- Molecular Formula: C10H16O3
- Molecular Weight: 184.23224
- EINECS: N/A
- Product Categories: N/A
- Mol File: 488150-84-1.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Propargyl-PEG1-t-butyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: Propargyl-PEG1-t-butyl ester(488150-84-1)
- EPA Substance Registry System: Propargyl-PEG1-t-butyl ester(488150-84-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 488150-84-1(Hazardous Substances Data)
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488150-84-1 Usage
Uses
Used in Pharmaceutical Industry:Propargyl-PEG1-t-butyl ester is used as a building block for the synthesis of complex molecules, particularly in the development of pharmaceutical compounds. Propargyl-PEG1-t-butyl ester's ability to form stable triazole linkages through Click Chemistry enables the creation of diverse molecular structures with potential therapeutic applications.
Used in Drug Delivery Systems:
In the field of drug delivery, Propargyl-PEG1-t-butyl ester serves as a versatile component for the design and synthesis of targeted drug delivery systems. Its reactivity in Click Chemistry allows for the precise attachment of drug molecules or targeting ligands to the delivery vehicle, potentially improving the efficacy and specificity of drug administration.
Used in Bioconjugation:
Propargyl-PEG1-t-butyl ester is used as a bioconjugation agent to attach biologically active molecules, such as peptides, proteins, or nucleic acids, to various surfaces or other molecular entities. The stable triazole linkage formed through Click Chemistry ensures the robust attachment of these biomolecules, which can be crucial for applications in diagnostics, therapeutics, and research.
Used in Material Science:
In the realm of material science, Propargyl-PEG1-t-butyl ester can be utilized as a component in the development of novel materials with specific properties. Propargyl-PEG1-t-butyl ester's ability to form stable linkages through Click Chemistry can be harnessed to create materials with tailored characteristics, such as improved mechanical strength, biocompatibility, or responsiveness to environmental stimuli.
Overall, Propargyl-PEG1-t-butyl ester is a versatile compound with a wide range of potential applications across various industries, including pharmaceuticals, drug delivery, bioconjugation, and material science. Its unique chemical properties, particularly its reactivity in Click Chemistry and the presence of a t-butyl protected carboxyl group, make it a valuable asset for the development of innovative solutions in these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 488150-84-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,8,1,5 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.Calculate Digit Verification of CAS Registry Number 488150-84:
(8*4)+(7*8)+(6*8)+(5*1)+(4*5)+(3*0)+(2*8)+(1*4)=181
181 % 10 = 1
So 488150-84-1 is a valid CAS Registry Number.
488150-84-1Upstream product
488150-84-1Downstream Products
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Propargyl-PEG1-t-butyl ester
