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3-(2-Propynyloxy)propanoic acid, also known as Propargyl-PEG1-acid, is a crosslinker with a propargyl group and a carboxylic acid group. The carboxylic acid reacts with primary amine under the activation of HATU or EDC, while the propargyl group can participate in copper-catalyzed azide-alkyne Click Chemistry reactions. 3-(2-Propynyloxy)propanoic acid contains a single PEG unit to help improve solubility.

55683-37-9

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55683-37-9 Usage

Uses

Used in Chemical Synthesis:
3-(2-Propynyloxy)propanoic acid is used as a crosslinker for chemical synthesis, enabling the attachment of molecules through copper-catalyzed click chemistry.
Used in Drug Delivery Systems:
3-(2-Propynyloxy)propanoic acid is used as a component in drug delivery systems to improve the solubility and stability of therapeutic agents.
Used in Bioconjugation:
3-(2-Propynyloxy)propanoic acid is used as a bioconjugation agent to attach biomolecules, such as peptides or proteins, to other molecules or surfaces through copper-catalyzed click chemistry.
Used in Polymer Science:
3-(2-Propynyloxy)propanoic acid is used as a monomer or crosslinker in polymer science to create functional polymers with specific properties.
Used in Surface Modification:
3-(2-Propynyloxy)propanoic acid is used for surface modification to attach functional groups or biomolecules to various surfaces, such as nanoparticles or sensors, through copper-catalyzed click chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 55683-37-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,8 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 55683-37:
(7*5)+(6*5)+(5*6)+(4*8)+(3*3)+(2*3)+(1*7)=149
149 % 10 = 9
So 55683-37-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H8O3/c1-2-4-9-5-3-6(7)8/h1H,3-5H2,(H,7,8)

55683-37-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-prop-2-ynoxypropanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:55683-37-9 SDS

55683-37-9Downstream Products

55683-37-9Relevant academic research and scientific papers

NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE

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Page/Page column 222-223, (2017/06/30)

The present invention relates to cryptophycin compounds of formula (I). The invention also relates to cryptophycin payloads, to cryptophycin conjugates, to compositions containing them and to their therapeutic use, especially as anticancer agents. The inv

Enantioselective tandem formation and [2,3]-sigmatropic rearrangement of cyclic propargylic oxonium ylides catalyzed by dirhodium(II) tetrakis[N-phthaloyl-(S)-tert-leucinate]

Tsutsui, Hideyuki,Matsuura, Maya,Makino, Kazuishi,Nakamura, Seiichi,Nakajima, Makoto,Kitagaki, Shinji,Hashimoto, Shunichi

, p. 283 - 295 (2007/10/03)

This paper describes the first examples of catalyst-dependent asymmetric induction in the periselective [2,3]-sigmatropic rearrangement of propargylic oxonium ylides generated by catalytic diazo decomposition. Catalysis of α-diazo-β-keto esters 4a-g using

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