488151-82-2

Upstream product

• 135-02-4 ortho-anisaldehyde 
• 1504-61-6 2-methoxycinnamyl alcohol 
• 79-22-1 methyl chloroformate 

Downstream Products

• 1136238-66-8 C₁₆H₁₆O 
• 1196721-88-6 C₂₃H₂₁FO₅S₂ 
• 1222181-31-8 3-(2-methoxyphenyl)-2-methylene-2,3-dihydro-1H-inden-1-one 
• 1421924-51-7 (S)-4-((R)-1-(2-methoxyphenyl)allyl)-4-methyl-2-phenyloxazol-5(4H)-one 

Relevant academic research and scientific papers

Intramolecular Sakurai Allylation of Geminal Bis(silyl) Enamide with Indolenine. A Diastereoselective Cyclization to Form Functionalized Hexahydropyrido[3,4- b]Indole

A fluoride-promoted intramolecular Sakurai allylation of geminal bis(silyl) enamide with indolenine has been developed. The reaction facilitates an efficient cyclization to give hexahydropyrido[3,4-b]indoles in good yields with high diastereoselectivity. The resulted cis, trans-stereochemistry further enables the ring-closing metathesis (RCM) reaction of two alkene moieties, giving a tetracyclic N-hetereocycle widely found as the core structure in akuammiline alkaloids.

Enantioselective α-functionalization of 1,3-dithianes by iridium-catalyzed allylic substitution

An iridium-catalyzed asymmetric allylic substitution reaction with 2-alkoxy carbonyl-1,3-dithianes has been achieved with high regio- and enantioselectivities. The transformation provides a new method for the enantioselective α-functionalization of dithianes. The corresponding dithiane-containing products are easily converted into many other derivatives with high yields and enantioselectivities.