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Dimethyl propargylphosphonate, also known as (3-chloropropyl)methyldimethylphosphonate, is an organophosphorus compound with the chemical formula C5H11ClO2P. It is a colorless liquid that is soluble in organic solvents and has a molecular weight of 170.57 g/mol. Dimethyl propargylphosphonate is primarily used as a chemical warfare agent, specifically as a nerve agent, due to its ability to inhibit the enzyme acetylcholinesterase, which is crucial for the proper functioning of the nervous system. It is highly toxic and can cause severe health issues, including respiratory failure and death, upon exposure. Dimethyl propargylphosphonate is also known by various other names, such as GA, which is an abbreviation for its Russian name "Gigant." It is important to handle this substance with extreme caution and in accordance with strict safety protocols due to its potential的危害性.

4885-44-3

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4885-44-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4885-44-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,8 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4885-44:
(6*4)+(5*8)+(4*8)+(3*5)+(2*4)+(1*4)=123
123 % 10 = 3
So 4885-44-3 is a valid CAS Registry Number.

4885-44-3Downstream Products

4885-44-3Relevant academic research and scientific papers

Carboranyl Oligonucleotides. 1. Synthesis of Thymidine(3',5')thymidine (o-Carboran-1-ylmethyl)phosphonate

Lesnikowski, Zbigniew J.,Schinazi, Raymond F.

, p. 6531 - 6534 (2007/10/02)

Using methyl (o-carboran-1-ylmethyl)phosphonate 6 as a novel and versatile borophosphonylating agent, 5'-O-(monomethoxytrityl)thymidine 3'-O- (8) and thymidine(3',5')thymidine (o-carboran-1-ylmethyl)phosphonate (12) were synthesized.The internucleotide (o-carboran-1-ylmethyl)phosphonate linkage was resistant to cleavage by phosphorodiesterases.The dinucleotide 12 represents a new class of modified lipophilic oligonucleotide-bearing carboranyl residue, designed as a carrier for boron neutron capture therapy and for potential use in antisense oligonucleotide technology.

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