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N-phenyl-N'-phenylsulfamoyl-urea, commonly known as Sulfamethoxazole, is a sulfa drug that functions as an antibiotic. It is utilized to treat or prevent specific bacterial infections by inhibiting bacterial growth. Often paired with trimethoprim to create the medication co-trimoxazole, Sulfamethoxazole is a widely-used and effective antibiotic in medical practice.

4886-26-4

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4886-26-4 Usage

Uses

Used in Pharmaceutical Industry:
Sulfamethoxazole is used as an antibiotic agent for treating a variety of bacterial infections. It is particularly effective against urinary tract infections, bronchitis, and travelers' diarrhea. The drug is available in oral and intravenous forms, catering to different administration routes for patient convenience and efficacy.
Used in Combination Therapy:
In combination with trimethoprim, Sulfamethoxazole is used as part of the drug co-trimoxazole, which leverages the synergistic effects of both antibiotics to enhance treatment outcomes against bacterial infections. This combination is particularly useful in managing infections that are resistant to single-agent therapies.
Used in Research and Development:
Sulfamethoxazole also serves as a subject for ongoing research and development in the field of antibiotic discovery. Scientists study its mechanisms of action and resistance patterns to develop new drugs and strategies to combat evolving bacterial strains.

Check Digit Verification of cas no

The CAS Registry Mumber 4886-26-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,8 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4886-26:
(6*4)+(5*8)+(4*8)+(3*6)+(2*2)+(1*6)=124
124 % 10 = 4
So 4886-26-4 is a valid CAS Registry Number.

4886-26-4Downstream Products

4886-26-4Relevant academic research and scientific papers

Solid phase synthesis of substituted aminosulfonyl ureas using a sulfonylcarbamate linker

Fitzpatrick, Louis J.,Rivero, Ralph A.

, p. 7479 - 7482 (1997)

A procedure for preparing substituted aminosulfonyl ureas on solid support is described. Chemoselective reaction of chlorosulfonyl isocyanate with the Wang resin followed by reaction with an amine provides resin-bound substituted aminosulfonylcarbamates. Heating of the resultant resin in THF with a second amine provides the desired substituted aminosulfonyl ureas in good yield and purity.

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