4887-42-7Relevant articles and documents
Synthesis method of N-hydroxymethyl-3, 4, 5, 6-tetrahydrophthalimide
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Paragraph 0010; 0030-0031; 0036-0041; 0046-0049, (2021/06/13)
The invention discloses a synthesis method of N-hydroxymethyl-3, 4, 5, 6-tetrahydrophthalimide, which comprises the following steps of adding phthalimide and tetrabutylammonium bromide into water, dropwise adding a formaldehyde aqueous solution after adding, carrying out heat preservation reaction after dropwise adding, drying a solvent after reaction, recrystallizing by using an acetone aqueous solution, putting the recrystallized material into a high-pressure kettle, adding Pd/C, introducing hydrogen, conducting heat preservation and pressure retaining reaction, desiccating the solvent and recrystallizing toluene after the reaction is finished. According to the method, the two-step synthesis yield of the method can reach 80% or above, and the normalized content of a product liquid spectrum can reach 97.6%. The solvent used in the method can be used in a reaction system after being recycled, the reduction catalyst can be used for more than 10 times, and the method is simple in process, easy to operate, high in reaction selectivity, low in product yield, quality and energy consumption and free of phosphorus and nitrogen-containing wastewater, the production field environment is remarkably improved, and industrial clean production is facilitated.
Process for producing cyclopropanecarboxylates
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, (2008/06/13)
There is disclosed a process process for producing a cyclopropanecarboxylate of formula (1): 1which process comprises reacting cyclopropanecarboxylic acid of formula (2): 2with a monohydroxy compound of formula (3): R6OH??(3),in the presence of a catalyst compound comprising an element of to Group 4 of the Periodic Table of Elements.