4887-90-5Relevant academic research and scientific papers
Convenient synthesis of benzothiazoles and benzimidazoles through bronsted acid catalyzed cyclization of 2-amino thiophenols/anilines with β-diketones
Mayo, Muhammad Shareef,Yu, Xiaoqiang,Zhou, Xiaoyu,Feng, Xiujuan,Yamamoto, Yoshinori,Bao, Ming
supporting information, p. 764 - 767 (2014/03/21)
Bronsted acid catalyzed cyclization reactions of 2-amino thiophenols/anilines with β-diketones under oxidant-, metal-, and radiation-free conditions are described. Various 2-substituted benzothiazoles/benzimidazoles are obtained in satisfactory to excellent yields. Different groups such as methyl, chloro, nitro, and methoxy linked on benzene rings were tolerated under the optimized reaction conditions.
Synthesis of 2-alkyl-substituted benzimidazoles by thermal decomposition of 2-azidobenzenamines in the presence of an aldehyde
Wallace, Jeffery M.,Soederberg, Bjoern C. G.,Hubbard, Jeremiah W.
, p. 3425 - 3439 (2007/10/03)
2-Substituted benzimidazoles were prepared by reaction of 2-azidoaminobenzenes with aldehydes under thermal conditions. The reaction probably proceeds via a sequential imine formation, azide decomposition forming a nitrene, and electrocyclization. Copyright Taylor & Francis Group, LLC.
