488702-38-1

Upstream product

• 2188-13-8 formaldehyde dipropargyl acetal 
• 171048-65-0 6-(3,5-dimethylbenzyl)-5-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 

Downstream Products

• 1187743-06-1 1-[({6-[(tert-butyl)diphenylsilyloxy]hexa-2,4-diynyl}oxy)methyl]-6-(3,5-dimethylbenzyl)-5-ethyl-1H-pyrimidine-2,4-dione 
• 1187743-01-6 6-(3,5-dimethylbenzyl)-5-ethyl-1-{[(3-thien-2-ylprop-2-ynyl)oxy]methyl}uracil 
• 1187742-97-7 6-(3,5-dimethylbenzyl)-5-ethyl-1-({[3-(4-nitrophenyl)prop-2-ynyl]oxy}methyl)uracil 
• 1187743-07-2 1-{[(3-{4-[(tert-butyl)diphenylsilyloxy]phenyl}prop-2-ynyl)oxy]methyl}-6-(3,5-dimethylbenzyl)-5-ethyluracil 
• 1187743-08-3 1-{[(3-{3-[(tert-butyl)diphenylsilyloxy]phenyl}prop-2-ynyl)oxy]methyl}-6-(3,5-dimethylbenzyl)-5-ethyluracil 
• 1187743-09-4 1-({[3-(4-{[(tert-butyl)diphenylsilyloxy]methyl}phenyl)prop-2-ynyl]oxy}methyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil 
• 1187742-90-0 6-(3,5-dimethylbenzyl)-5-ethyl-1-{[(3-phenylprop-2-ynyl)oxy]methyl}uracil 
• 1187742-99-9 6-(3,5-dimethylbenzyl)-5-ethyl-1-({[3-(3-cyanophenyl)prop-2-ynyl]oxy}methyl)uracil 
• 1187742-96-6 6-(3,5-dimethylbenzyl)-5-ethyl-1-({[3-(2-nitrophenyl)prop-2-ynyl]oxy}methyl)uracil 
• 1187742-98-8 6-(3,5-dimethylbenzyl)-5-ethyl-1-[({3-[2-(trifluoromethyl)phenyl]prop-2-ynyl}oxy)methyl]uracil 
• 1187743-00-5 1-[({3-[3,5-bis(trifluoromethyl)phenyl]prop-2-ynyl}oxy)methyl]-6-(3,5-dimethylbenzyl)-5-ethyluracil 
• 1187742-95-5 6-(3,5-dimethylbenzyl)-5-ethyl-1-[({3-[(2-methylsulfanyl)phenyl]prop-2-ynyl}oxy)methyl]uracil 
• 1187742-91-1 6-(3,5-dimethylbenzyl)-5-ethyl-1-{[(3-phenanthren-9-ylprop-2-ynyl)oxy]methyl}uracil 
• 1187743-05-0 2-bromo-N-[4-(3-{[6-(3,5-dimethylbenzyl)-5-ethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]methoxy}prop-1-ynyl)phenyl]acetamide 

Relevant academic research and scientific papers

Synthesis of novel N-1 (allyloxymethyl) analogues of 6-benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, emivirine) with improved activity against HIV-1 and its mutants

This paper reports the synthesis and the antiviral activities of a series of 6-arylmethyl-1-(allyloxymethyl)-5-alkyluracil derivatives, which can be viewed as analogues of the anti-HIV-1 drug emivirine (formerly MKC-442) from which they differ in the repl