488713-30-0

Basic information

• Product Name: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-
• Synonyms: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-;3-Chloro-5-nitro-2-pyridinecarbonitrile;3-Chloro-5-nitropyridine-2-carbonitrile;3-Chloro-2-cyano-5-nitropyridine
• CAS NO: 488713-30-0
• Molecular Formula: C6H2ClN3O2
• Molecular Weight: 183.554
• Mol File: 488713-30-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-(488713-30-0)
• EPA Substance Registry System: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-(488713-30-0)

Safety Data

• Hazardous Substances Data: 488713-30-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research and Development:
3-Chloro-5-nitro-2-pyridinecarbonitrile is used as a research compound for the synthesis and study of various organic molecules. Its unique structure allows for the exploration of new chemical reactions and the development of novel compounds with potential applications in various fields.
Used in Pharmaceutical Industry:
3-Chloro-5-nitro-2-pyridinecarbonitrile is used as an intermediate in the synthesis of pharmaceutical compounds. Its presence in the molecular structure can contribute to the development of new drugs with improved properties, such as increased efficacy or reduced side effects.
Used in Material Science:
3-Chloro-5-nitro-2-pyridinecarbonitrile is used as a building block in the development of new materials with specific properties, such as improved thermal stability or enhanced electrical conductivity. Its incorporation into the molecular structure of these materials can lead to the creation of innovative products with applications in various industries.

Upstream product

• 488713-29-7 3-chloro-2-iodo-5-nitropyridine 
• 22353-40-8 2,3-dichloro-5-nitropyridine 
• 1941-27-1 tetrabutylammonium nitrate 
• 38180-46-0 3-chloro-2-cyanopyridine 

Downstream Products

• 488713-31-1 5-amino-3-chloro-2-cyanopyridine 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.

HETEROCYCLIC COMPOUND

The present invention provides a heterocyclic compound having an RORγt inhibitory action. The present invention relates to a compound represented by the formula (I): wherein Ar is a the partial structure (1) to the partial structure (5), Q is a bivalent group selected from the group consisting of (Ia)-(If), and B is a ring optinally having substituent(s), or a salt thereof.

Bicyclic modulators of androgen receptor function

The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention.

BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION

The invention provides compounds according to formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention.

Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds.

2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS

The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.