488799-67-3 Usage
Uses
Used in Pharmaceutical Research and Development:
4-[(5-Bromo-2-fluorophenyl)methyl]morpholine is utilized as a chemical building block for the synthesis of potential drug candidates. Its unique structure allows for the exploration of structure-activity relationships, which is crucial in optimizing the efficacy and safety of new medications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-[(5-Bromo-2-fluorophenyl)methyl]morpholine serves as a valuable component in the design and study of novel compounds. The bromo and fluoro substitutions on the phenyl group provide versatility for chemical modifications, facilitating the investigation of how these changes impact the compound's biological activity.
Used in Drug Discovery:
4-[(5-Bromo-2-fluorophenyl)methyl]morpholine is employed as a starting material in drug discovery processes. Its morpholine moiety can impart beneficial pharmacokinetic properties to drug molecules, such as improved solubility and bioavailability, which are essential for the development of effective therapeutic agents.
Used in Structure-Activity Relationship Studies:
4-[(5-Bromo-2-fluorophenyl)methyl]morpholine is used as a key component in structure-activity relationship studies. The ability to modify the bromo and fluoro substitutions on the phenyl group allows researchers to examine how these changes affect the compound's interaction with biological targets, which is vital for the optimization of drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 488799-67-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,8,7,9 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 488799-67:
(8*4)+(7*8)+(6*8)+(5*7)+(4*9)+(3*9)+(2*6)+(1*7)=253
253 % 10 = 3
So 488799-67-3 is a valid CAS Registry Number.
488799-67-3Relevant academic research and scientific papers
KINASE INHIBITORS
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Paragraph 0267; 0268, (2015/03/04)
Disclosed are compounds having [1,2,4]triazolo[4,3-a]pyridine groups and pharmaceutically acceptable salts thereof. The compounds are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
DERIVATIVES OF 4-HYDROXY-1,2,3,4-TETRAHYDRONAPHTALEN-1-YL UREA AND THEIR USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT
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Page/Page column 75, (2013/06/27)
Disclosed are compounds having [1,2,4]triazolo[4,3-a] pyridine groups and pharmaceutically acceptable salts thereof. The compounds are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
THIAZOLYL-DIHYDRO-INDAZOLES
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Page/Page column 40, (2009/10/22)
The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a
