488816-96-2

Basic information

• Product Name: Pyrimidine, 2-chloro-4-(2-naphthalenyl)-
• CAS NO: 488816-96-2
• Molecular Formula: C14H9ClN2
• Molecular Weight: 240.692
• Mol File: 488816-96-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyrimidine, 2-chloro-4-(2-naphthalenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimidine, 2-chloro-4-(2-naphthalenyl)-(488816-96-2)
• EPA Substance Registry System: Pyrimidine, 2-chloro-4-(2-naphthalenyl)-(488816-96-2)

Safety Data

• Hazardous Substances Data: 488816-96-2(Hazardous Substances Data)

Usage

General Description

Pyrimidine, 2-chloro-4-(2-naphthalenyl)- is a chemical compound with the molecular formula C15H10ClN3. It is a derivative of pyrimidine and contains a 2-chloro-4-(2-naphthalenyl) moiety. Pyrimidine, 2-chloro-4-(2-naphthalenyl)- has potential applications in the pharmaceutical industry, as pyrimidines are known for their diverse biological activities. It may be used in the synthesis of various drugs and pharmaceutical compounds for their potential therapeutic properties. More research is needed to fully understand the specific uses and potential effects of this chemical compound.

Upstream product

• 3934-20-1 2,6-Dichloropyrimidine 
• 32316-92-0 naphthalene-2-boronic acid 
• 1084835-11-9 sodium 4-(naphthalene-2-yl)pyrimidin-2-olate 
• 1722-12-9 2-chloropyrimidine 
• 4541-70-2 2-naphthyllithium 

Downstream Products

• 1123231-07-1 WAY-262611 
• 1114991-95-5 4-{[4-(2-naphthyl)pyrimidin-2-yl]amino}benzenesulfonamide 

Relevant articles and documents

Redox deracemization of phosphonate-substituted dihydropyrimidines

An efficient redox deracemization of the phosphonic ester substituted 3,4-dihydropyrimidin-2-one (DHPM) derivatives is described. The one-pot deracemization strategy consisted of the oxidization to destroy the stereocenter center and the following asymmetric transfer hydrogenation to regenerate the chiral carbon center with the vicinal phosphonic ester group, providing a series of optically active phosphonate substituted DHPMs with up to 96% ee.

Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors

Sphingosine-1-phosphate is now emerging as an important player in cancer, inflammation, autoimmune, neurological and cardiovascular disorders. Abundance evidence in animal and humans cancer models has shown that SphK1 is linked to cancer. Thus, there is a

(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: A wingless β-catenin agonist that increases bone formation rate

A high-throughput screening campaign to discover small molecule leads for the treatment of bone disorders concluded with the discovery of a compound with a 2-aminopyrimidine template that targeted the Wnt β-catenin cellular messaging system. Hit-tolead in