488846-76-0

Usage

Molecular weight

299.40 g/mol

Physical state

White crystalline solid

Functional groups

Ester, Piperazine, Boc-protecting group

Uses

As a reagent in organic chemistry for the synthesis of pharmaceuticals and other organic compounds, typically used as a protecting group in peptide synthesis.

Stability

Relatively stable

Handling

Flammable, can cause irritation to skin, eyes, and respiratory system if not handled properly.

Upstream product

• 542-69-8 1-iodo-butane 
• 76003-29-7 4-(t-butyloxycarbonyl)piperazin-2-one 
• 107-06-2 1,2-dichloro-ethane 
• 31954-27-5 N-(tert-butoxycarbonyl)glycine methyl ester 

Downstream Products

• 59702-09-9 1-butyl-piperazin-2-one 

Relevant academic research and scientific papers

PIPERAZINYL ANTIVIRAL AGENTS

Provided are compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).

N-(3-amino-2-hydroxy-propyl) substd. alkylamidoalkanol compd.

Disclosed are compounds of the formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.