489398-73-4Relevant academic research and scientific papers
Silica-supported synthesis of some 1,3,5-trisubstituted 2-pyrazolines under solvent-free and microwave irradiation conditions
Azarifar, Davood,Maleki, Behrooz
, p. 157 - 159 (2005)
A simple method for the synthesis of 2-pyrazolines is described which occurs on silica surface under solvent-free conditions within 110-180 sec using microwave irradiation. The results obtained indicate that the use of silica gel as a support in pyrazolin
Novel synthesis of 1,3,5-trisubstituted 2-pyrazolines promoted by chlorotrimethylsilane
Xie, Zengyang,Bian, Xiaoqin,Geng, Xin,Li, Shuangshuang,Wang, Cunde
, p. 52 - 54 (2008/09/19)
1,3,5-Trisubstituted-2-pyrazolines were effectively synthesised by utilising chlorotrimethylsilane as an efficient promoter in the cyclisation addition of Phenylhydrazine to chalcones under nitrogen in acetonitrile. The clean, mild reaction conditions, high yields and a simple workup of target compounds were attractive features of the reaction which enables a facile preparative procedure for building the pyrazoline ring.
Convenient synthesis of highly functionalized pyrazolines via mild, photoactivated 1,3-dipolar cycloaddition
Wang, Yizhong,Rivera Vera, Claudia I.,Lin, Qing
, p. 4155 - 4158 (2008/02/12)
A mild, photoactivated 1,3-dipolar cycloaddition procedure was successfully developed for the synthesis of polysubstituted pyrazolines. This procedure involved the in situ generation of the reactive nitrile imine dipoles using a hand-held UV lamp at 302 n
