489399-30-6Relevant academic research and scientific papers
Facile one-pot three-component synthesis of 4,6-diaryl-3,4-dihydropyrimidine-2(1H)-thiones under ultrasonic irradiation
Abbass, Shymaa A.,Moustafa, Gamal A. I.,Hassan, Heba A.,Abuo-Rahma, Gamal El-Din A.
supporting information, p. 2995 - 3000 (2019/08/22)
We developed a facile one-pot procedure for the synthesis of 4,6-diaryl-3,4-dihydropyrimidine-2(1H)-thione under ultrasonic irradiation. The method is based on a three components reaction of aldehydes, ketones, and thiourea under basic conditions affordin
Synthesis and antiprotozoal activity of 1,2,3,4-tetrahydro-2- thioxopyrimidine analogs of combretastatin A-4
Desta, Dereje,Sjoholm, Robert,Lee, Lauren,Lee, Megan,Dittenhafer, Kristin,Canche, Sarah,Babu, Balaji,Chavda, Sameer,Dewar, Christie,Yanow, Stephanie,Best, Aaron A.,Lee, Moses
scheme or table, p. 364 - 369 (2012/06/05)
Eighteen 1,2,3,4-tetrahydro-2-thioxopyrimidine analogs (5a-j, 6a-e, and 7a-c) of combretastatin A-4 were synthesized with the objective of discovering compounds capable of controlling the growth of Trypanosoma lewisii, Leishmania tarantole, Plasmodium fal
