489429-47-2

Upstream product

• 33301-43-8 2-Bromo-1,4-dimethylnaphthalene 
• 571-58-4 1,4-dimethylnaphthalene 
• 139962-95-1 2-formyl-4-methoxyphenylboronic acid 
• 7507-86-0 2-bromo-5-methoxy-benzaldehyde 
• 489429-46-1 (1,4-dimethylnaphthalen-2-yl)boronic acid 

Downstream Products

• 671780-71-5 2-(4-methoxy-2-[2-methoxyvinyl]phenyl)-1,4-dimethylnaphthalene 

Relevant academic research and scientific papers

Microwave-assisted suzuki cross-coupling reaction, a key step in the synthesis of polycyclic aromatic hydrocarbons and their metabolites

(Chemical Equation Presented) A highly efficient and general method for Suzuki cross-coupling reaction en route to the synthesis of polycyclic aromatic hydrocarbons (PAHs) and their metabolites has been developed. Microwave irradiation of aryl bromides 1

Synthesis of the o-Quinones and Other Oxidized Metabolites of Polycyclic Aromatic Hydrocarbons Implicated in Carcinogenesis

Efficient new syntheses of the o-quinone derivatives of benzo[a]pyrene (BPQ), 7,12-dimethylbenz-[a] anthracene (DMBAQ), and benz[a]anthracene (BAQ), implicated as active carcinogenic metabolites of the parent polycyclic aromatic hydrocarbons (PAHs), are reported. These PAH quinones also serve as starting compounds for the synthesis of the other active metabolites of these PAHs thought to be involved in their mechanism(s) of carcinogenesis. The latter include the corresponding o-catechols, trans-dihydrodiols, and the corresponding anti- and syn-diol epoxides.