Cas 489437-63-0,Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-4-(3-oxobutyl) -, (2R)-

489437-63-0

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Basic information

Product Name: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-4-(3-oxobutyl) -, (2R)-
Synonyms:
CAS NO:489437-63-0
Molecular Formula: C26H25F6N3O2
Molecular Weight: 525.494
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-4-(3-oxobutyl) -, (2R)-(CAS DataBase Reference)
NIST Chemistry Reference: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-4-(3-oxobutyl) -, (2R)-(489437-63-0)
EPA Substance Registry System: Piperazine, 1-[3,5-bis(trifluoromethyl)benzoyl]-2-(1H-indol-3-ylmethyl)-4-(3-oxobutyl) -, (2R)-(489437-63-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 489437-63-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 489437-63-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,9,4,3 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 489437-63:
(8*4)+(7*8)+(6*9)+(5*4)+(4*3)+(3*7)+(2*6)+(1*3)=210
210 % 10 = 0
So 489437-63-0 is a valid CAS Registry Number.

489437-63-0Upstream product

489437-63-0Downstream Products

489437-63-0Relevant academic research and scientific papers

Piperazinyl oxime ethers as NK-1 receptor antagonists

Van Den Hoogenband, Adri,Van Maarseveen, Jan H.,McCreary, Andrew C.,Mulder, Arie T.,Van Scharrenburg, Guus J. M.,Van Stuivenberg, Herman H.,Zethof, Theo J. J.,Zijta, Barbara,Iwema Bakker, Wouter I.

, p. 1045 - 1048 (2007/10/03)

The synthesis and structure-activity relations for a new class of centrally active NK-1 receptor antagonists are described. The new compounds are based on piperazine 2 and contain an oxime ether functionality. Several new compounds have high affinity for

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