489461-78-1Relevant academic research and scientific papers
Synthesis and activity of 4,5-diarylimidazoles as human CB1 receptor inverse agonists
Plummer, Christopher W.,Finke, Paul E.,Mills, Sander G.,Wang, Junying,Tong, Xinchun,Doss, George A.,Fong, Tung M.,Lao, Julie Z.,Schaeffer, Marie-Therese,Chen, Jing,Shen, Chun-Pyn,Stribling, D. Sloan,Shearman, Lauren P.,Strack, Alison M.,Van Der Ploeg, Lex H.T.
, p. 1441 - 1446 (2005)
Structure-activity relationship studies directed toward the optimization of 4,5-diarylimidazole-2-carboxamide analogs as human CB1 receptor inverse agonists resulted in the discovery of the two amide derivatives 24a and b (hCB1 IC50 = 6.1 and 4
