489468-61-3

Upstream product

• 40064-34-4 piperidine-4,4-diol hydrochloride 
• 138900-24-0 1-(4-fluorophenyl)-5-bromo-1H-indole 
• 41979-39-9 4-piperidone hydrochloride 
• 352-34-1 4-fluoro-1-iodobenzene 
• 10075-50-0 5-bromo-1H-indole 

Downstream Products

• 489468-63-5 4-[1-(4-fluorophenyl)-5-(1-methyl-tetrazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-68-0 4-[1-(4-fluorophenyl)-5-(1-methyl-1,3,4-triazol-2-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 243467-66-5 4-[1-(4-fluorophenyl)-5-(2-methyl-tetrazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-69-1 4-[1-(4-fluorophenyl)-5-(1-methyl-1,2,4-triazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-74-8 4-[1-(4-fluorophenyl)-5-(1-methyl-1,2,3-triazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective α1 adrenoceptor antagonists

A new class of 5-heteroaryl-substituted 1-(4-fluorophenyl)-3-(4-piperidinyl)-1H-indoles as highly selective and potentially CNS-active α1-adrenoceptor antagonists is described. The compounds are derived from the antipsychotic sertindole. The st

Synthesis and structure-affinity relationship investigations of 5-aminomethyl and 5-carbamoyl analogues of the antipsychotic sertindole. A new class of selective α1 adrenoceptor antagonists

A new class of selective α1 adrenoceptor antagonists derived from the antipsychotic drug sertindole is described. The most potent and selective compound 1-(2-{4-[5-aminomethyl-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl} ethyl)-2-imidazolid