243467-66-5Relevant articles and documents
5-heteroaryl substituted indoles
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, (2008/06/13)
The present invention relates to compounds having general formula (I) as defined herein, or a pharmaceutically acceptable acid addition salt thereof. The compounds are selective α1-adrenoceptor ligands.
Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective α1 adrenoceptor antagonists
Balle, Thomas,Perregaard, Jens,Ramirez, Martha Teresa,Larsen, Anna Kirstine,S?by, Karina Kr?jer,Liljefors, Tommy,Andersen, Kim
, p. 265 - 283 (2007/10/03)
A new class of 5-heteroaryl-substituted 1-(4-fluorophenyl)-3-(4-piperidinyl)-1H-indoles as highly selective and potentially CNS-active α1-adrenoceptor antagonists is described. The compounds are derived from the antipsychotic sertindole. The st