4906-27-8Relevant academic research and scientific papers
Highly efficient and selective deprotection method for prenyl, geranyl, and phytyl ethers and esters using borontrifluoride-etherate
Narender,Venkateswarlu,Madhur,Reddy, K. Papi
, p. 26 - 33 (2012/10/30)
An efficient, simple, and practical method has been developed for the deprotection of prenyl, geranyl, and phytyl ethers and esters of aromatic and aliphatic compounds using borontrifluoride-etherate (BF3· OEt2) at room temperature in good to excellent yields for the first time. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
A general and efficient catalyst for palladium-catalyzed C-O coupling reactions of aryl halides with primary alcohols
Gowrisankar, Saravanan,Sergeev, Alexey G.,Anbarasan, Pazhamalai,Spannenberg, Anke,Neumann, Helfried,Beller, Matthias
supporting information; experimental part, p. 11592 - 11598 (2010/10/02)
An efficient procedure for palladium-catalyzed coupling reactions of (hetero)aryl bromides and chlorides with primary aliphatic alcohols has been developed. Key to the success is the synthesis and exploitation of the novel bulky di-1-adamantyl-substituted bipyrazolylphosphine ligand L6. Reaction of aryl halides including activated, nonactivated, and (hetero)aryl bromides as well as aryl chlorides with primary alcohols gave the corresponding alkyl aryl ethers in high yield. Noteworthy, functionalizations of primary alcohols in the presence of secondary and tertiary alcohols proceed with excellent regioselectivity.
