491-74-7

Basic information

• Product Name: C10465
• Synonyms: C10465;7-(β-D-Glucopyranosyloxy)-5-hydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;Irigenin 7-beta-D-glucopyranoside;Irigenin 7-glucoside;Irigenin-7-O-beta-D-glucopyranoside;Lridin;Irigenin-7-O-β-D-glucopyranoside
• CAS NO: 491-74-7
• Molecular Formula: C₂₄H₂₆O₁₃
• Molecular Weight: 522.45544
• Mol File: 491-74-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 208℃
• Boiling Point: 833.5°Cat760mmHg
• Flash Point: 284.1°C
• Appearance: /
• Density: 1.558±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 1.85E-29mmHg at 25°C
• Refractive Index: 1.659
• Storage Temp.: 2-8°C
• PKA: 5.96±0.20(Predicted)
• CAS DataBase Reference: C10465(CAS DataBase Reference)
• NIST Chemistry Reference: C10465(491-74-7)
• EPA Substance Registry System: C10465(491-74-7)

Safety Data

• Hazardous Substances Data: 491-74-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 491-74-7 differently. You can refer to the following data:
1. dual Src/Abl tyrosine kinase inhibitor with potent antiproliferative activity
2. Iridin is isolated from the iris species which exhibits antioxidant and antidiabetic activity and an α-amylase inhibitor. Lactate dehydrogenase inhibitor.

Definition

ChEBI: A glycosyloxyisoflavone that is irigenin substituted by a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.

InChI:InChI=1/C24H26O13/c1-32-13-5-9(4-11(26)22(13)33-2)10-8-35-12-6-14(23(34-3)19(29)16(12)17(10)27)36-24-21(31)20(30)18(28)15(7-25)37-24/h4-6,8,15,18,20-21,24-26,28-31H,7H2,1-3H3/t15-,18-,20+,21-,24-/m1/s1

Downstream Products

• 50-99-7 D-glucose 
• 78134-86-8 5,7-dihydroxy-6,3',4',5'-tetramethoxyisoflavone 

Relevant articles and documents

Long-chain fatty acid acylated derivatives of isoflavone glycosides from the rhizomes of Iris domestica

Six undescribed long-chain fatty acid esters of isoflavone glycosides were obtained from the rhizomes of Iris domestica (L.). Their structures were elucidated by comprehensive spectroscopic data, alkaline hydrolysis, and acid hydrolysis. This is the first report of the long-chain (C14–C18) fatty acid derivatives of isoflavone glycosides from natural products. Belamcandnoate B and D exhibited moderate cytotoxic activities against HCT-116, HepG2, and BGC823 cell lines with IC50 values of 1.69–6.86 μM. Belamcandnoate B and E exhibited 72.27 and 58.98% inhibitory activities, respectively, against Fe2+/cysteine-induced liver microsomal lipid peroxidation at a concentration of 10 μM.