492-79-5 Usage
Uses
Used in Pharmaceutical or Biochemical Applications:
[R-(R,R)]-2-(2,2-dichloroacetamido)-3-hydroxy-3-(p-nitrophenyl)ethyl benzoate is used as a potential pharmaceutical or biochemical agent due to its complex structure, which may allow for specific interactions with biological molecules.
Used in Research and Development:
[R-(R,R)]-2-(2,2-dichloroacetamido)-3-hydroxy-3-(p-nitrophenyl)ethyl benzoate is used as a research tool for studying enzymatic processes or drug interactions, given its complex structure and potential for specific interactions.
Used in Drug Development:
[R-(R,R)]-2-(2,2-dichloroacetamido)-3-hydroxy-3-(p-nitrophenyl)ethyl benzoate is used in drug development for the discovery and design of new pharmaceuticals, as its structure may provide unique properties or interactions that could be beneficial in treating various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 492-79-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 492-79:
(5*4)+(4*9)+(3*2)+(2*7)+(1*9)=85
85 % 10 = 5
So 492-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H16Cl2N2O6/c1-2-27-16(23)12-4-3-9-17(24,13(12)20-15(22)14(18)19)10-5-7-11(8-6-10)21(25)26/h3-8,14,24H,2,9H2,1H3,(H,20,22)/t17-/m1/s1
492-79-5Relevant academic research and scientific papers
Enzymatic regioselective production of chloramphenicol esters
Bizerra, Ayla M.C.,Montenegro, Tasso G.C.,Lemos, Telma L.G.,De Oliveira, Maria C.F.,De Mattos, Marcos C.,Lavandera, Iván,Gotor-Fernández, Vicente,De Gonzalo, Gonzalo,Gotor, Vicente
, p. 2858 - 2862 (2011/05/12)
An enzymatic study has been performed in the search for synthetic routes to produce chloramphenicol derivatives through regioselective processes using lipases. Complementary transesterification and hydrolytic reactions have been carried to synthesize chloramphenicol regioisomers. Reaction parameters, such as biocatalyst, solvent, acyl donor, and temperature have been optimised in order to obtain chloramphenicol esters with high yields through acylation processes. Scale-up of the enzymatic reactions (1 g-scale at 0.25 M) and catalyst recycling (up to 10 cycles) have been successfully achieved. Furthermore, monoacylated derivatives at the more hindered secondary position could also be obtained employing hydrolysis processes.
