4923-53-9

Basic information

• Product Name: 6-Hydroxynaphthalene-1,4-dione
• Synonyms: 6-Hydroxy-1,4-naphthoquinone;6-Hydroxynaphthalene-1,4-dione;7-Hydroxy-1,4-naphthoquinone
• CAS NO: 4923-53-9
• Molecular Formula: C₁₀H₆O₃
• Molecular Weight: 174.15
• Mol File: 4923-53-9.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Hydroxynaphthalene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Hydroxynaphthalene-1,4-dione(4923-53-9)
• EPA Substance Registry System: 6-Hydroxynaphthalene-1,4-dione(4923-53-9)

Safety Data

• Hazardous Substances Data: 4923-53-9(Hazardous Substances Data)

Upstream product

• 575-38-2 1,7-Dihydroxynaphthalene 
• 135-19-3 β-naphthol 
• 54125-02-9 danishefsky's diene 
• 106-51-4 p-benzoquinone 
• 4826-65-7 4-amino-naphthalene-1,6-diol 
• 53589-65-4 naphthalene-1,4,6-triol 
• 575-44-0 1,6-dihydroxynaphthalene 

Downstream Products

• 83312-50-9 2-hydroxy-6-methyl-9,10-anthraquinone 
• 83312-51-0 7-hydroxy-2-methylanthraquinone 
• 1192354-89-4 6-hydroxy-2-phenyl-1,4-naphthoquinone 
• 31039-62-0 2,6-dihydroxynaphthalene-1,4-dione 
• 78758-31-3 2-anilino-6-hydroxy-[1,4]naphthoquinone 

Relevant articles and documents

Strategies towards the synthesis of 6-N,N-diethylcarbamyloxy-1,4-dimethoxy- 7-naphthylboronic acid

After acetylation, condensation between Danishefsky's diene and benzoquinone afforded a stable methoxytriacetoxydihydronaphthalene intermediate, which was subsequently transformed by the Snieckus DOM protocol into the regiospecific 7-naphthylboronic acid.

Synthesis, biological evaluation, and correlation of cytotoxicity versus redox potential of 1,4-naphthoquinone derivatives

A series of 1,4-naphthoquinone derivatives of lawsone (1), 6-hydroxy-1,4-naphthoquinone (2), and juglone (3) were synthesized by alkylation, acylation, and sulfonylation reactions. The yields of lawsone derivatives 1a-1k (type A), 6-hydroxy-1,4-naphthoqui

Oxidative Dearomatization of Phenols and Polycyclic Aromatics with Hydrogen Peroxide Triggered by Heterogeneous Sulfonic Acids

We report herein a method for the oxidative dearomatization of phenols and bare polycyclic arenes into the corresponding quinoid derivatives using hydrogen peroxide. The reaction is catalyzed by sulfonic acids and best results were achieved using heterogenized species. The best results using phenols were achieved using a hybrid material, namely a perfluorinated polymer functionalized with sulfonic acid groups supported on silica. The dearomatization of polycyclic aromatic hydrocarbons performed better using the polymeric acid catalyst. These methods operate under mild conditions, using mild and benign oxidants and thus minimizing the formation of waste.