492470-99-2

Upstream product

• 7217-59-6 2-Methoxybenzenethiol 
• 14500-40-4 2-bromo-2-phenyl-1-(p-tolyl)ethanone 
• 405201-45-8 2-(2-methoxy-phenylsulfanyl)-2-phenyl-1-p-tolyl-ethanone 

Downstream Products

• 492471-11-1 1-(7-hydroxy-2-phenyl-3-p-tolyl-benzo[b]thiophen-6-yl)-ethanone 
• 405201-29-8 2-phenyl-3-p-tolyl-benzo[b]thiophen-7-ol 

Relevant academic research and scientific papers

A facile synthesis of 7,8-di aryl coumarino and flavano benzo-thiophenes

The key step for the synthesis of 7-hydroxy 2,3-diarylsubstituted benzothiophenes 5a-f, by starting from substituted 2-aryl-2-((2-methoxy phenyl)thio)acetophenones 3a-f as an intermediate, consists of a Friedel-Crafts cyclization followed by demethylation by Lewis acids like BF3OEt2 and AlCl3 in DCM.