4926-14-1

Basic information

• Product Name: 5-Methyl-3-phenyl-1,2,4-triazolo[4,3-a]pyridine
• Synonyms: 5-Methyl-3-phenyl-1,2,4-triazolo[4,3-a]pyridine
• CAS NO: 4926-14-1
• Molecular Formula: C₁₃H₁₁N₃
• Molecular Weight: 209.2465
• Mol File: 4926-14-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.19g/cm³
• Refractive Index: 1.657
• CAS DataBase Reference: 5-Methyl-3-phenyl-1,2,4-triazolo[4,3-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-3-phenyl-1,2,4-triazolo[4,3-a]pyridine(4926-14-1)
• EPA Substance Registry System: 5-Methyl-3-phenyl-1,2,4-triazolo[4,3-a]pyridine(4926-14-1)

Safety Data

• Hazardous Substances Data: 4926-14-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H11N3/c1-10-6-5-9-12-14-15-13(16(10)12)11-7-3-2-4-8-11/h2-9H,1H3

Upstream product

• 5315-24-2 1-(6-methylpyridin-2-yl)hydrazine 
• 611-73-4 Benzoylformic acid 
• 109-06-8 α-picoline 
• 100-52-7 benzaldehyde 
• 1456807-58-1 2-hydrazino-6-methylpyridine hydrochloridehydrate 
• 5333-86-8 ethyl benzimidate hydrochloride 

Relevant articles and documents

Method for preparing 3-phenyl-[1,2,4] triazole [4,3-a] pyridine compound without metal catalysis

The invention discloses a method for preparing a 3-phenyl-[1,2,4] triazole [4,3-a] pyridine compound without metal catalysis. The method comprises the following steps: enabling a pyridine compound, sodium azide and a benzaldehyde compound to react suffici

[1,2,4]-triazol [4,3-a] pyridines compound and synthesis method thereof

The invention discloses a [1,2,4]-triazol [4,3-a] pyridines compound and a synthesis method thereof. The compound has a structure general formula shown as the formula (I), wherein R1 is selected fromaryl and heterocyclic groups; R2 is selected from hydrogen, alkyl, alkoxy, halogen or aryl. According to the synthesis method, alpha-ketonic acid and 2-hydrazinopyridine are used as raw materials; KIis used as a catalyst; Na2CO3 is used as alkali; TBHP is used as an oxidizing agent; 1,4-dioxane is used as a solvent; after a series of serial connection cyclization and decarboxylation aromatization, the [1,2,4]-triazol [4,3-a] pyridines compound is obtained. The [1,2,4]-triazol [4,3-a] pyridines compound is prepared under the condition of no transition metal and has the advantages that the reaction is efficient and fast; the conditions are mild; the substrate is simple and can be easily obtained; the applicability is wide; the reaction time is short; the yield is high, and the like; meanwhile, the post treatment of the reaction is simple and convenient; the harm to experiment operators is reduced; the environment-friendly effect is achieved; the green chemical requirements are met.