493019-22-0Relevant academic research and scientific papers
8-(Methyltosylaminoethynyl)-1-naphthyl (MTAEN) Glycosides: Potent Donors in Glycosides Synthesis
Zhou, Si-Yu,Hu, Xin-Ping,Liu, Hui-Juan,Zhang, Qing-Ju,Liao, Jin-Xi,Tu, Yuan-Hong,Sun, Jian-Song
supporting information, p. 653 - 657 (2022/01/20)
With 8-(methyltosylaminoethynyl)-1-naphthyl (MTAEN) glycoside as donors, a novel and efficient glycosylation protocol has been established. The MTAEN glycosylation protocol exhibits the merits of shelf-stable donors, mild catalytic promotion conditions, considerably extended substrate scope encompassing both free alcohols, silylated alcohols, nucleobases, primary amides, and C-type nucleophile acceptors, and applicability to various one-pot strategies for highly efficient synthesis of oligosaccharides, such as orthogonal one-pot, single-catalyst one-pot, and acceptor reactivity-controlled one-pot strategies.
Synthesis of (1→6)-β-D-glucosamine hexasaccharide, a potential antitumor and immunostimulating agent
Yang, Feng,He, Hongmei,Du, Yuguo
, p. 7561 - 7563 (2007/10/03)
(1→6)-β-D-Glucosamine hexasaccharide was synthesized convergently using isopropyl thioglycosides as glycosyl donors in all coupling steps. The target compound showed good antitumor activity based on mice S180 model studies.
