493033-95-7

Upstream product

• 493033-92-4 6-bromo-3,4-bis-O-(tert-butyldimethylsilyl)-2,6-dideoxy-2-iodo-β-D-glucopyranosyl fluoride 
• 493033-94-6 (2R,3S,4R,7S,8R,9R,10R,11S)-2,8-di-[(tert-butyldimethyl)silyloxy]-3,7,9-trimethyl-10-[(benzoyl)oxy]-11-methoxy-13-trimethylsilyl-tridec-4-ol-12-yn-6-one 
• 98-88-4 benzoyl chloride 
• 251301-00-5 (2R,3S)-3-[(-O-tert-Butyldimethylsilyl)oxy]-2-methylbutan-1-ol 
• 140223-32-1 (2S,3R)-3-(tert-butyldimethylsilanyloxy)-2-methylbutyraldehyde 
• 370066-70-9 [3S,4R,5R,6S,7R,8R]-6-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-5,7-dimethyl-3-methoxy-8-[(triethylsilyl)oxy]-1-trimethylsilylnon-1-yne 
• 749900-19-4 (3S,4R,5R,6R,7S)-3,5-dimethyl-4-[(tert-butyldimethyl)siloxy]-6-[(benzoyl)oxy]-7-methoxynon-8-yn-2-one 
• 493034-00-7 (3S,4R,5R,6R,7S)-3,5-dimethyl-4-[(tert-butyldimethyl)silyloxy]-6-[(benzoyl)oxy]-7-methoxy-non-8-yn-2-one 

Downstream Products

• 749900-27-4 (2R,3S,4R,7S,8R,9R,10R,11S)-2,8-bis-[(tert-butyldimethyl)silyloxy]-3,7,9-trimethyl-4-O-[2,6-deoxy-3,4-bis-O-(tert-butyldimethyl)silyl-β-D-glucopyranosyl]-10-[(benzoyl)oxy]-11-methoxy-13-trimethylsilyl-tridec-4-ol-12-yn-6-one 

Relevant academic research and scientific papers

Total synthesis of formamicin

The enantioselective total synthesis of the cytotoxic plecomacrolide natural product formamicin (1) is described. Key aspects of this synthesis include the efficient transacetalation reactions of MOM ethers 28 and 38 to form the seven-membered formyl acet

2-Deoxy-2-iodo-beta-glucopyranosyl fluorides: mild and highly stereoselective glycosyl donors for the synthesis of 2-deoxy-beta-glycosides from beta-hydroxy ketones.

2-Deoxy-2-iodo-beta-glucopyranosyl fluoride 14 is a highly stereoselective glucopyranosyl donor that may be activated under mild conditions. Application of this new glycosyl donor to the glycosidation reactions of a variety of acceptors including beta-hyd