493038-47-4Relevant academic research and scientific papers
One-pot four-component reaction for the generation of pyrazoles and pyrimidines
Stonehouse, Jeffrey P.,Chekmarev, Dmitriy S.,Ivanova, Natalya V.,Lang, Stuart,Pairaudeau, Garry,Smith, Neal,Stocks, Michael J.,Sviridov, Sergey I.,Utkina, Lyubov M.
, p. 100 - 104 (2008/09/21)
The palladium-catalysed four-component coupling of a halide, terminal alkyne, molybdenum hexacarbonyl and either a hydrazine or amidine has been shown to be an efficient method for the construction of highly substituted pyrazoles and pyrimidines, respectively, in a one-pot process. Georg Thieme Verlag Stuttgart.
New flexible synthesis of pyrazoles with different, functionalized substituents at C3 and C5
Grotjahn, Douglas B.,Van, Sang,Combs, David,Lev, Daniel A.,Schneider, Christian,Rideout, Marc,Meyer, Christoph,Hernandez, Genaro,Mejorado, Lupe
, p. 9200 - 9209 (2007/10/03)
Syntheses of pyrazoles featuring a functionalized side chain attached to carbon 3 and varying alkyl and aryl substituents attached to carbon 5 are presented. Installation of R = methyl, isopropyl, tert-butyl, adamantyl, or phenyl groups at C5 is reported
