4931-08-2

Basic information

• Product Name: N′-(pyridin-2-yl)benzamidine
• Synonyms: N′-(pyridin-2-yl)benzamidine
• CAS NO: 4931-08-2
• Molecular Weight: 197.239
• Mol File: 4931-08-2.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: N′-(pyridin-2-yl)benzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N′-(pyridin-2-yl)benzamidine(4931-08-2)
• EPA Substance Registry System: N′-(pyridin-2-yl)benzamidine(4931-08-2)

Safety Data

• Hazardous Substances Data: 4931-08-2(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 825-60-5 benzimidic acid ethyl ester 
• 100-47-0 benzonitrile 

Downstream Products

• 33863-66-0 4-methyl-N-(3-phenyl-4-pyridin-2-yl-4H-[1,2,4]thiadiazol-5-ylidene)-benzamide 
• 33863-69-3 phenyl-(3-phenyl-4-pyridin-2-yl-4H-[1,2,4]thiadiazol-5-ylidene)-amine 
• 1236223-42-9 6-(4-bromophenyl)-4-(morpholin-4-yl)-2-phenylpyridine-3-carbonitrile 
• 1236223-46-3 6-(4-chlorophenyl)-4-(morpholin-4-yl)-2-phenylpyridine-3-carbonitrile 
• 1236223-29-2 2',6'-diphenyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-carbonitrile 
• 1236223-57-6 6-(4-chlorophenyl)-2-phenyl-4-(pyrrolidin-1-yl)pyridine-3-carbonitrile 
• 1236223-54-3 6'-(4-chlorophenyl)-2'-phenyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-3'-carbonitrile 
• 1236223-60-1 6'-(4-methoxyphenyl)-2'-phenyl-3,4,5,6-tetrahydro-2H-[1,4]bipyridinyl-3-carbonitrile 
• 6935-27-9 N-benzylpyridin-2-amine 
• 55-21-0 benzamide 
• 4589-12-2 N-(pyrid-2-yl)benzamide 
• 614-28-8 N-benzoylbenzamide 
• 33957-35-6 2-phenyl-pyrido<1,2-a>-1,3,5-triazin-4-one 
• 779-24-8 2-phenyl[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

Transition-Metal-Free Synthesis of 1,2-diphenyl-1H-benzo[d] Imidazole Derivatives from N-phenylbenzimidamides and Cyclohexanones

A transition-metal-free strategy for the formation of 1,2-diphenyl-1H-benzo[d] imidazoles from N-phenylbenzimidamides and cyclohexanones is introduced. This is the first report on the direct synthesis of 1,2-diphenyl-1H-benzo[d] imidazoles from cyclohexanones and N-phenylbenzimidamides via iodine- promoted oxidative cyclization. Non-aromatic cyclohexanones were smoothly dehydrogenated, and acted as an aryl source using oxygen as a green oxidant. The catalytic use of iodine makes this method quite simple, more economical and convenient. Under optimized conditions, various substituted 1,2-diphenyl-1H-benzo[d] imidazoles were smoothly reacted, and the desired substituted imidazoles were generated with moderate to excellent yields. (Figure presented.).

PhI(OAc) 2 -Mediated Regioselective Synthesis of 5-Guanidino-1,2,4-thiadiazoles and 1,2,4-Triazolo[1,5- a ]pyridines via Oxidative N-S and N-N Bond Formation

An effective and expeditious approach for the construction of biologically important 5-guanidino-1,2,4-thiadiazole and 1,2,4-triazolo[1,5- a ]pyridine derivatives has been developed. This new protocol involves the phenyliodine(III) diacetate [PhI(OAc) su

Vanadium-Catalyzed Oxidative C(CO)-C(CO) Bond Cleavage for C-N Bond Formation: One-Pot Domino Transformation of 1,2-Diketones and Amidines into Imides and Amides

A novel vanadium-catalyzed one-pot domino reaction of 1,2-diketones with amidines has been identified that enables their transformation into imides and amides. The reaction proceeds by dual acylation of amidines via oxidative C(CO)-C(CO) bond cleavage of 1,2-diketones to afford N,N′-diaroyl-N-arylbenzamidine intermediates. In the reaction, these intermediates are easily hydrolyzed into imides and amides through vanadium catalysis. This method provides a practical, simple, and mild synthetic approach to access a variety of imides as well as amides in high yields. Moreover, one-step construction of imide and amide bonds with a long-chain alkyl group is an attractive feature of this protocol.