4931-29-7

Usage

Uses

Used in Pharmaceutical Industry:
[1,2,4]Triazolo[1,5-a]pyridine, 5-methyl-2-phenylis used as a compound in the pharmaceutical industry for its potential role in the development of new drugs and medicines. Its unique structure and properties make it a valuable candidate for further research and potential therapeutic uses.
Used in Drug Development:
[1,2,4]Triazolo[1,5-a]pyridine, 5-methyl-2-phenylis used as a key component in drug development for its potential to contribute to the creation of novel therapeutic agents. [1,2,4]Triazolo[1,5-a]pyridine, 5-methyl-2-phenyl-'s specific structural features may offer new avenues for targeting various medical conditions and improving treatment options.

Upstream product

• 62135-66-4 N-(6-methylpyridin-2-yl)benzamide 
• 1824-81-3 2-Amino-6-methylpyridine 
• 100-47-0 benzonitrile 
• 39996-42-4 1-amino-2-methylpyridinium mesitylenesulfonate 

Relevant academic research and scientific papers

Synthetic method 1, 2 and 4 - triazole compound

The invention discloses 1. 2,4 - Triazole compound synthesis method belongs to the technical field of synthesis of triazole compounds. After the reaction is finished, the reaction is carried out under the heating condition, and the target product 1, 2 and

A Convenient Synthesis of 1,5-Fused 1,2,4-Triazoles from N-Arylamidines via Chloramine-T Mediated Intramolecular Oxidative N-N Bond Formation

A convenient synthesis of 1,5-fused 1,2,4-triazoles from readily available N-arylamidines is reported. The reaction is efficiently promoted by chloramine-T to afford the desired products mostly in high yields and in relatively short time, through direct m

Trichloroisocyanuric acid-mediated synthesis of 1,5-fused 1,2,4-triazoles from N-heteroaryl benzamidines via intramolecular oxidative N–N bond formation

A convenient synthesis of 1,5-fused 1,2,4-triazoles from readily available N-heteroaryl benzamidines is reported. The reaction is efficiently promoted by trichloroisocyanuric acid to afford the desired products, mostly in high yields and in relatively sho

I2/KI-Mediated Oxidative N-N Bond Formation for the Synthesis of 1,5-Fused 1,2,4-Triazoles from N -Aryl Amidines

An I2/KI-mediated oxidative N-N bond formation reaction is described. This new and environmentally benign approach allows for the convenient synthesis of a variety of 1,2,4-triazolo[1,5-a]pyridines and other 1,5-fused 1,2,4-triazoles from readi

Non-steroidal pregnancy-terminating agents: Design, synthesis and structure-activity relationships of 2-aryl-1,2,4-triazolo[1,5-a]pyridine

The syntheses and the pregnancy-terminating activity relationships of compounds 5a-n are reported. Compounds 5b and 5l are found to be more potent than DL-111 - a known drug having effective pregnancy-terminating activity in vitro. Further research shows compounds 5b and 5l have the same activity as DL-111 in vivo. We also found an exciting result that they have excellent anti-implantation activity after oral administration.