4938-65-2Relevant academic research and scientific papers
Synthesis and characterization of novel bi- and tricyclic α-amino acids
Johnson, Matthew R.,Gauuan, Jolicia F.,Guo, Cheng,Guzzo, Peter R.,Le, Van-Duc,Shenoy, Rajesh A.,Hamby, James,Roark, Howard,Stier, Michael,Mangette, John E.
experimental part, p. 2769 - 2793 (2011/08/22)
As part of a medicinal chemistry collaboration, a number of novel bi- and tricyclic aamino acids were prepared through various routes and characterized by 1 H nuclearOverhauser effect difference experiments. The syntheses provide a number of routes to access some highly substituted amino acid derivatives that have not been reported previously. It is envisaged that the chemistry described here could be applied to the synthesis of other unique substrates Taylor & Francis Group, LLC.
